White Matter and Stress Reduction Effects of Mindfulness Training
正念训练的白质和减压效果
基本信息
- 批准号:10706459
- 负责人:
- 金额:$ 12.02万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-09-19 至 2025-08-31
- 项目状态:未结题
- 来源:
- 关键词:AffectAmygdaloid structureBehaviorBehavior TherapyBehavioral MechanismsBrainBrain MappingBrain regionCellular PhoneCollaborationsCross-Sectional StudiesDataData SetDiffusionDiffusion Magnetic Resonance ImagingDoctor of PhilosophyEmployeeEnvironmentFacultyFosteringFunctional Magnetic Resonance ImagingGoalsGrantHealthHealth BenefitHealth PsychologyImaging technologyInflammationInterventionLearningLinkLiteratureMapsMeasuresMediatingMentorsMethodsMindfulness TrainingModelingNational Center for Complementary and Integrative HealthNeuronal PlasticityNeurosciencesNucleic Acid Regulatory SequencesOutcomePathway interactionsPatient Self-ReportPersonsPhysiologicalPopulationProblem SolvingPsychologyRandomized, Controlled TrialsRegulationRegulatory PathwayResearchResearch DesignResearch PersonnelResourcesRewardsRisk ReductionSamplingScanningSocial PsychologyStimulusStressStructureTechniquesTestingTrainingTraining ProgramsUniversitiesWorkWritingactive controlbrain basedburnoutcareercomparison controlconditioned fearemotional stimulusexpectationexperienceexperimental studyinterestmindfulnessmindfulness interventionmindfulness meditationmindfulness-based stress reductionmultimodalityneuralneuroimagingneuromechanismperceived stresspost interventionprogramsresponseskillssmartphone applicationsocialspectrographstatistical learningstress reactivitystress reductionwhite matter
项目摘要
PROJECT SUMMARY
Janine M. Dutcher, PhD aims to understand the brain mechanisms for behavioral interventions for stress reduction and
health. The research and training plan described in this proposal will strengthen her experience in neuroimaging with
additional training in structural neuroimaging, and launch her independent career as a multi-modal health neuroscientist.
To enable this training, Dr. Dutcher will analyze data from a randomized controlled trial (RCT) of mindfulness training in
stressed employees. This study features functional and structural neuroimaging, and stress assessments—and experience
with these data will help the PI build a career that explores the brain mechanisms for stress reduction interventions.
Candidate: Dr. Dutcher is a Special Faculty Researcher in the Psychology department at Carnegie Mellon University
(CMU). She received her doctorate at UCLA in social and health psychology. Her work focused on understanding the
neural mechanisms of stress reduction, the neuroscience of inflammation and social experience, and the relationship
between reward and stress. She has worked primarily on cross-sectional and experimental studies, using functional
neuroimaging methods for testing neural mechanisms. She plans to receive training in structural neuroimaging and RCTs
to advance her studies on the longitudinal brain mechanisms for behavioral interventions.
Training Goals: Dr. Dutcher aims to learn more about RCT study design, intervention integrity, and mindfulness
meditation programs—goals that her mentor Dr. Creswell can aid in. Analytically, Dr. Dutcher will receive training in
diffusion spectrum imaging from Dr. Verstynen, learning statistical techniques for linking longitudinal structural and
functional brain changes, and assessing those relationships as a mechanism for the benefits that interventions have on
stress and health. Finally, Dr. Dutcher will hone the professional skills that will support her pathway to independence,
including grant writing, networking, and more mentoring opportunities through managing research teams.
Mentors/Environment: Dr. Dutcher has overseen the day-to-day execution of an RCT exploring the effects of a
mindfulness training program on stress and burnout in a stressed employee population with Dr. Creswell. She and Dr.
Verstynen coordinated to add diffusion spectrum and functional neuroimaging pre- and post-intervention. Thus, she will
be leveraging an existing dataset and existing collaborations to achieve her training and research goals. She has the
resources and support of CMU, proximity to other collaborators, and the ideal mentoring team for executing this proposal.
Research: Although the literature has established mindfulness as an effective stress reduction intervention, the brain
mechanisms are as yet unclear. The purpose of this project is to analyze data from a rigorous RCT of a 30-day smartphone
mindfulness program compared to an active control program (problem solving) to evaluate how mindfulness changes the
brain in a sample of stressed employees (N=100). Analyses will examine changes in white matter integrity over the 30-
day intervention, compared to control, and link these changes in white matter to changes in stress. This project has the
potential for mapping the brain mechanisms for stress reduction, providing greater understanding of how to effectively
intervene and reduce the risk of stress-related health conditions in the population.
项目总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Janine Michele Dutcher其他文献
Janine Michele Dutcher的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Janine Michele Dutcher', 18)}}的其他基金
White Matter and Stress Reduction Effects of Mindfulness Training
正念训练的白质和减压效果
- 批准号:
10348862 - 财政年份:2022
- 资助金额:
$ 12.02万 - 项目类别: