Administrative Core

项目摘要 行政核心是行政、培训、协调和监督部门， 布里格姆妇女医院（BWH）临床研究核心中心（CCCR）。BWH CCCR，VERITY （使用生物信息学和高级分析的流变学价值和证据），利用 BWH和哈佛医学院（HMS）的资源，为临床社区提供服务 由NIAMS使命在当地和国家确定的调查人员。提供的服务 方法学核心和生物信息学核心响应已确定的需求，以更好地获得完整的 一系列的临床研究方法组织在一个精简和易于访问的格式。基础上 由于前一个资助周期的成功，行政核心包含一个增强的强化计划， 通过面对面和虚拟远程学习提供广泛的课程，旨在培训和指导 儿科和成人风湿和肌肉骨骼（MSK）临床研究人员，当地和全国。的 具体的强化计划产品是根据我们在前一个周期的经验和来自以下方面的调查数据提供的 研究社区。VERITY行政核心的总体目标是继续建立 并维持一个由受训人员、初级和高级调查人员组成的社区， 目的是改善风湿性和MSK疾病的治疗和结局。行政核心 为方法学核心和生物信息学资源的各个方面提供科学监督 核心这些目标是通过以下具体目标实现的：1.促进和监督 方法学核心和生物信息学资源核心的科学和行政工作，确保 以有效和负责任的方式满足研究社区的需求; 2.培养下 风湿性和肌肉骨骼疾病的成人和儿科临床研究人员的一代， 加强对URiM能力建设的重视。在VERITY的前4年多，教师培训， 指导了40多名初级教员和学员。培训模式包括： 两年一度的VERITY临床研究课程和迷你课程;通过强大的本地和 国家计划;为初级教师和受训人员提供大幅折扣的核心服务;试点和可行性补助金 计划;和一系列研讨会与基于网络的流。总而言之，VERITY行政核心 提供有效的科学和行政监督，以确保方法的最佳使用 和生物信息学资源核心服务。丰富计划吸引，教育，并指导 下一代临床研究人员，以加强儿童和成人风湿性和MSK疾病的研究， 美方此外，行政核心与其他NIAMS CCCR合作， 网站改善服务的研究社区。

PROJECT SUMMARY The Administrative Core represents the executive, training, coordinating, and oversight component of the Brigham and Women’s Hospital (BWH) Core Centers for Clinical Research (CCCR). The BWH CCCR, VERITY (Value and Evidence in Rheumatology using bioInformaTics, and advanced analYtics), leverages the resources of BWH and Harvard Medical School (HMS) to offer services to the community of clinical investigators defined by the NIAMS mission, locally and nationally. The services provided by the Methodology Core and Bioinformatics Core respond to identified needs for better access to a complete array of clinical research methods organized in a streamlined and readily accessible format. Building on the success of the prior cycle of funding, the Administrative Core contains an enhanced Enrichment Program with wide course offering through both face-to-face and virtual distance learning, aiming to train and mentor pediatric and adult rheumatic and musculoskeletal (MSK) clinical researchers, locally and nationally. The specific Enrichment Program offerings are informed by our experiences in the prior cycle and survey data from the Research Community. The overall purpose of the VERITY Administrative Core is to continue to build and maintain a community of trainees, junior, and senior investigators working toward the common goal of improving treatment and outcomes of rheumatic and MSK disease. The Administrative Core provides scientific oversight for all aspects of the Methodology Core and Bioinformatics Resource Core. These objectives are accomplished through the following Specific Aims: 1. To facilitate and supervise the scientific and administrative work of the Methodology Core and Bioinformatics Resource Core, ensuring that the needs of the Research Community are met in an efficient and responsible manner; 2. To train the next generation of adult and pediatric clinical researchers in rheumatic and musculoskeletal diseases, with an increased focus on URiM capacity building. During the first 4+ years of VERITY, the faculty trained and mentored over 40 junior faculty and trainees. The modes of training have included: formal pedagogy through the biennial VERITY Clinical Research Course and mini-courses; 1:1 mentoring through a robust local and national program; heavily discounted Core services for junior faculty and trainees; a Pilot & Feasibility grant program; and a series of seminars with web-based streaming. In sum, the VERITY Administrative Core provides effective scientific and administrative oversight to ensure optimal use of the Methodology and Bioinformatics Resource Core services. The Enrichment Program attracts, educates, and mentors the next generation of clinical researchers to enhance pediatric and adult rheumatic and MSK disease research in the US. Furthermore, the Administrative Core collaborates with other NIAMS CCCRs to create synergy across sites improving services for the Research Community.