Administrative Core

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PROJECT SUMMARY The Administrative Core represents the executive, training, coordinating, and oversight component of the Brigham and Women’s Hospital (BWH) Core Centers for Clinical Research (CCCR). The BWH CCCR, VERITY (Value and Evidence in Rheumatology using bioInformaTics, and advanced analYtics), leverages the resources of BWH and Harvard Medical School (HMS) to offer services to the community of clinical investigators defined by the NIAMS mission, locally and nationally. The services provided by the Methodology Core and Bioinformatics Core respond to identified needs for better access to a complete array of clinical research methods organized in a streamlined and readily accessible format. Building on the success of the prior cycle of funding, the Administrative Core contains an enhanced Enrichment Program with wide course offering through both face-to-face and virtual distance learning, aiming to train and mentor pediatric and adult rheumatic and musculoskeletal (MSK) clinical researchers, locally and nationally. The specific Enrichment Program offerings are informed by our experiences in the prior cycle and survey data from the Research Community. The overall purpose of the VERITY Administrative Core is to continue to build and maintain a community of trainees, junior, and senior investigators working toward the common goal of improving treatment and outcomes of rheumatic and MSK disease. The Administrative Core provides scientific oversight for all aspects of the Methodology Core and Bioinformatics Resource Core. These objectives are accomplished through the following Specific Aims: 1. To facilitate and supervise the scientific and administrative work of the Methodology Core and Bioinformatics Resource Core, ensuring that the needs of the Research Community are met in an efficient and responsible manner; 2. To train the next generation of adult and pediatric clinical researchers in rheumatic and musculoskeletal diseases, with an increased focus on URiM capacity building. During the first 4+ years of VERITY, the faculty trained and mentored over 40 junior faculty and trainees. The modes of training have included: formal pedagogy through the biennial VERITY Clinical Research Course and mini-courses; 1:1 mentoring through a robust local and national program; heavily discounted Core services for junior faculty and trainees; a Pilot & Feasibility grant program; and a series of seminars with web-based streaming. In sum, the VERITY Administrative Core provides effective scientific and administrative oversight to ensure optimal use of the Methodology and Bioinformatics Resource Core services. The Enrichment Program attracts, educates, and mentors the next generation of clinical researchers to enhance pediatric and adult rheumatic and MSK disease research in the US. Furthermore, the Administrative Core collaborates with other NIAMS CCCRs to create synergy across sites improving services for the Research Community.