More effective therapeutic targeting of high risk childhood cancer: Neuroblastoma as a model

高风险儿童癌症的更有效治疗靶向：神经母细胞瘤作为模型

• 批准号: nhmrc : 1132608
• 负责人: Prof Glenn Marshall
• 金额: $ 446.33万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Program Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/effective-therapeutic-targeting-neuroblastoma-model/948679
• 关键词: More; effective; therapeutic; targeting; risk

Cancer is the commonest cause of death from disease in Australian children. Childhood neuroblastoma is a particularly aggressive cancer, for which new treatment approaches are urgently needed. The team aims to discover better safer therapies for children with this cancer, conducting clinical trials using new drugs and novel drug combinations. We will also investigate novel ways of targeting neuroblastoma cells and identify therapeutic targets in neuroblastoma-initiating cells.

癌症是澳大利亚儿童因疾病死亡的最常见原因。儿童神经母细胞瘤是一种特别具有侵袭性的癌症，迫切需要新的治疗方法。该团队旨在为患有这种癌症的儿童发现更好、更安全的疗法，使用新药和新药物组合进行临床试验。我们还将研究靶向神经母细胞瘤细胞的新方法，并确定神经母细胞瘤起始细胞的治疗靶点。