Coordinating Center for Research Centers for Improving Management of Symptoms During and Following Cancer Treatment

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Project Summary To advance the Beau Biden Cancer MoonshotSM Initiative to accelerate cancer research and the Blue Ribbon Panel’s recommendation to minimize cancer treatment’s debilitating side effects, RTI International will continue to serve as the Coordinating Center (CC) for the Research Centers (RCs) for Improving Management of Symptoms Across Cancer Treatments (IMPACT) Consortium. As the CC, RTI will provide leadership, scientific expertise, and logistical support to the consortium projects that seek to improve symptom management across the cancer treatment continuum (i.e., treatment with curative intent, treatment with noncurative/palliative intent, cancer survivorship) and address the unique challenges of minority and medically underserved populations. Specifically, we will enhance research efficiency, productivity, and impact by facilitating collaboration and providing the logistical, communications, and operational support necessary to run a multicenter research Consortium; facilitate the development of evidence-based symptom management recommendations based on results across studies and research sites; and accelerate adoption of integrated systems for monitoring and managing patient-reported symptoms by collaborating with RCs to broadly disseminate findings. This application has specific strengths that will enhance the scientific productivity of the Consortium. The CC will foster collaboration within the IMPACT Consortium by uniting diverse researchers around shared goals and harmonized studies. RTI will promote effective communication by developing and maintaining custom web- based tools for communications and document sharing. RTI will leverage data standards and harmonization across the Consortium to catalyze data sharing and aggregation.