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Implementing a Community-Engaged Amputation Prevention Intervention in Rural Patients with Diabetes and Peripheral Arterial Disease

对农村糖尿病和周围动脉疾病患者实施社区参与的截肢预防干预措施

基本信息

批准号：
10820093
负责人：
Samantha D Minc
金额：
$ 5.39万
依托单位：
WEST VIRGINIA UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-01 至 2026-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10820093
关键词：
Achievement Address Amputation Area Award Blood Vessels Cardiovascular Diseases Clinic Clinic Visits Clinical Investigator Clinical Sciences Collaborations Communities Community Outreach Complications of Diabetes Mellitus Consolidated Framework for Implementation Research Country County Data Diabetes Mellitus Diabetic Foot Disparity Education Effectiveness of Interventions Event Evidence based intervention Foot Ulcer Foundations Funding Future Geographic Locations Geography Goals Guidelines Health Health Disparities Research Hotlines Intervention K-Series Research Career Programs Knowledge Limb structure Location Mentored Patient-Oriented Research Career Development Award Mentors Mentorship Methods Operative Surgical Procedures Outcome Patients Pattern Peripheral arterial disease Practice Guidelines Preparation Prevalence Provider Quality of Care Recommendation Research Research Personnel Risk Risk Factors Rural Rural Community Rural Health Rural Population Self Efficacy Societies Specialist Surgeon Testing Training Translating Translational Research Translations Vascular Diseases Wait Time West Virginia Work acceptability and feasibility barrier to care care coordination career career development community engagement cultural competence design effectiveness study foot health disparity high risk implementation intervention implementation research improved innovation intervention refinement multidisciplinary patient population preservation prevent preventive intervention randomized trial research data dissemination rural area rural health clinic rural patients skills therapy design videoconference

项目摘要

Amputation is a devastating but preventable complication of diabetes (DM) and peripheral arterial disease (PAD); it serves as a marker for severe cardiovascular disease and for disparities in quality of care. Although rural populations have multiple risk factors for amputation, there is a critical gap in amputation research in rural communities, with very little data available on amputation prevention interventions designed to meet the needs of these communities to improve health outcomes. West Virginia (WV), a highly rural state with some of the highest national prevalence rates of DM and cardiovascular disease, is a location in great need of innovative solutions to prevent these complications. My long-term career goal is to become a clinician-investigator in health disparities research focused on designing and implementing community-engaged interventions that will reduce amputation rates in patients with DM and PAD. My preliminary work in this area demonstrated that DM and PAD-related amputation rates in WV are up to 6 times higher than the national average. Moreover, despite adjusting for multiple risk factors, the risk of amputation is clustered in certain high-risk geographic regions in WV. This Mentored Career Development Training Award (K23) is the ideal opportunity for me to obtain the skills, training and mentorship needed to achieve this goal. The objective of this study is to develop, implement and assess an amputation prevention intervention designed for use in high-risk rural areas using community engagement approaches. I will test the central hypothesis that an amputation prevention intervention developed and implemented in a community-engaged fashion will be feasible and acceptable for use in high-risk rural areas. The specific aims of this study are to: 1) develop a provider-based amputation prevention intervention appropriate for high-risk rural areas using community engagement approaches, 2) implement and assess the feasibility and acceptability of the collaboratively-developed, provider-based amputation prevention intervention using the Consolidated Framework for Implementation Research (CFIR) and refine the intervention based on these findings, and 3) translate and disseminate findings to community Stakeholders, and then widely to other high-risk rural areas to prepare for implementation of a multi-area intervention effectiveness study. Guided by a strong multidisciplinary mentorship team and an active Community Engagement and Outreach Core with an established Provider-Based Research Network through the WV Clinical and Translational Science Institute, I am poised to successful conduct this research plan in rural WV. The training and research plan for this K23 award will enable me to achieve my long-term career goal, to become a leader in vascular surgery with both expertise in limb preservation and designing and implementing community-engaged interventions to address vascular disease-related health disparities.

截肢是糖尿病（DM）和外周动脉疾病的一种破坏性但可预防的并发症

项目成果

期刊论文数量（6）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Mixed methods research: A primer for the vascular surgeon.

DOI：
10.1053/j.semvascsurg.2022.09.003
发表时间：
2022-12
期刊：
Seminars in vascular surgery
影响因子：
2.5
作者：
通讯作者：

The role of intervention and implementation research to LEAP vascular surgery forward in our approach to the patient with amputation and health equity.

LEAP 血管手术的干预和实施研究在我们治疗截肢患者和健康公平方面发挥着重要作用。

DOI：
10.1016/j.jvs.2023.11.036
发表时间：
2024
期刊：
Journal of vascular surgery
影响因子：
4.3
作者：
Minc,SamanthaDanielle
通讯作者：
Minc,SamanthaDanielle

A review of disparities in peripheral artery disease and diabetes-related amputations during the COVID-19 pandemic.

DOI：
10.1053/j.semvascsurg.2022.12.002
发表时间：
2023-03
期刊：
Seminars in vascular surgery
影响因子：
2.5
作者：
通讯作者：

Resection of a hormonally active carotid body tumor.

切除激素活性颈动脉体肿瘤。

DOI：
10.1016/j.avsurg.2023.100185
发表时间：
2023
期刊：
Annals of vascular surgery. Brief reports and innovations
影响因子：
0
作者：
Evans,Megan;Minc,Samantha;Almenoff,Maxwell
通讯作者：
Almenoff,Maxwell

Community-engaged research in vascular surgery: An approach to decrease amputation disparities and effect population-level change.

社区参与的血管外科研究：减少截肢差异和影响人口水平变化的方法。

DOI：
10.1053/j.semvascsurg.2022.12.001
发表时间：
2023
期刊：
Seminars in vascular surgery
影响因子：
2.5
作者：
Minc,SamanthaDanielle;Powell,Chloé;Drudi,LauraM;Young,Laura;Kempe,Kelly;Ochoa,Lyssa;Peek,Monica;Dino,Geri
通讯作者：
Dino,Geri