Cornell Roybal Center-Translational Research Institute on Pain in Lather Life

项目摘要--总体 在过去的5年里，康奈尔的罗伊巴尔中心-关于晚年生活中的疼痛的翻译研究所 (TRIPLL)为行为翻译开发了创新的方法和有效的基础设施 和社会科学研究，以改善老年人的健康和福祉。TRIPLL的一个主要优势是 它展示了将行为和社会科学研究与现实世界背景联系起来的能力。TRIPLL有 专注于开发行为干预措施并利用新技术 疼痛背景下的适应性行为变化，这是一个由医学研究所作为 极其重要且未得到充分解决的公共卫生问题。在此续订申请中，我们将在我们的 迄今取得的成就，通过可衡量地扩大中心的基础设施，以增强 开发有效的、可扩展的疼痛行为干预措施，并特别注重实施这一点 对代表性不足的人群，即有认知障碍的老年人、少数族裔老年人、 居住在农村的老年人，以及那些感染艾滋病毒的老年人。这种关注是合理的，因为疼痛非常普遍， 在老年人中，特别是在代表性不足的人群中，费用高昂，而且往往使人残疾。行为 干预措施(如心理和运动疗法)现在通常被鼓励作为主要治疗方法。 对于疼痛，但需要研究以提高其疗效、有效性和长期益处。康奈尔大学 Roybal Center将通过以下方式在以往成功的基础上再接再厉：1)开设新的导师管道；2)扩大 研究人员、商业实体和社区利益相关者支持中心支持的翻译 研究；以及3)利用行为改变科学和传播科学领域的进展 使用NIH阶段模型开发和测试创新的行为干预措施，以指导他们的发展 和评估。康奈尔大学罗伊巴尔中心的首要目标将是：1)开发强大且可扩展的 解决晚年疼痛问题的行为干预；2)指导充满活力的调查员 开发计划；3)提供有效的基础设施，以便使用新的 能够增强干预效果的技术；以及4)利用智力、财政和其他资源 这一应用程序中的学术合作者，从而获得了任何人都无法达到的结果 一家机构。扩大了伊萨卡和伊萨卡著名研究中心之间的多学科合作 纽约市(NYC)，包括威尔·康奈尔和康奈尔科技公司以及三个新的战略合作伙伴( 康奈尔大学研究办公室老龄化和技术改进研究和教育中心 评估和密歇根城市非裔美国人老龄化研究中心)，构成了一个主要的 这份续签申请的实力。

Project Summary – Overall Over the past 5 years, Cornell’s Roybal Center–The Translational Research Institute on Pain in Later Life (TRIPLL) has developed innovative approaches and an effective infrastructure for the translation of behavioral and social science research to improve the health and well-being of older adults. A major strength of TRIPLL is its demonstrated ability to link behavioral and social science research to real world contexts. TRIPLL has focused on developing behavioral interventions and on leveraging new technologies that can bring about adaptive behavior change in the context of pain, an issue characterized by the Institute of Medicine as a critically important and under-addressed public health problem. In this renewal application, we will build on our accomplishments to date by measurably expanding the infrastructure of the Center to augment the development of potent and scalable behavioral interventions for pain, with a particular focus on conducting this research with underrepresented populations, i.e., older persons with cognitive impairment, minority elders, rural-dwelling older adults, and those aging with HIV.!This focus is justified because pain is highly prevalent, costly, and frequently disabling in older adults, particularly among underrepresented populations. Behavioral interventions (e.g., psychological and exercise therapies) are now routinely encouraged as primary treatments for pain, but research is needed to enhance their efficacy, effectiveness and long-term benefits. Cornell’s Roybal Center will build on prior successes by: 1) opening new mentee pipelines; 2) expanding networks of researchers, commercial entities and community stakeholders to support the translation of Center-supported research; and 3) leveraging advances in the fields of behavior change science and communication science to develop and test innovative behavioral interventions using the NIH Stage Model to guide their development and evaluation. The overarching aims of Cornell’s Roybal Center will be to: 1) Develop potent and scalable behavioral interventions to address the problem of later-life pain; 2) Conduct a vibrant investigator development program; 3) Provide an effective infrastructure for developing behavioral interventions using new technologies that can enhance intervention effects; and 4) Leverage the intellectual, fiscal, and other resources of the academic collaborators in this application, thereby achieving results that would not be attainable by any one institution. The expanded multi-disciplinary collaboration among prominent research centers in Ithaca and New York City (NYC), including Weill Cornell and Cornell Tech along with three new strategic partners (the Center for Research and Education on Aging and Technology Enhancement, the Cornell Office for Research on Evaluation, and the Michigan Center for Urban African American Aging Research), constitutes a major strength of this renewal application.