Stroke Trials Network-Regional Coordinating Center University of Pittsburgh (STN-UP)

中风试验网络-匹兹堡大学区域协调中心 (STN-UP)

• 批准号: 10847050
• 负责人: MARCELO ROCHA
• 金额: $ 7.95万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2023-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10847050
• 关键词: Acute; Admission activity; Adopted; Adult; Advisory Committees; Ambulatory Care Facilities; Area; Award; Catchment Area; Childhood; Childhood stroke; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Clinical Trials Network; Collaborations; Communities; Community Hospitals; Consultations; Data Coordinating Center; Discipline; Education; Emergency Care; Enrollment; Ensure; Equity; Ethnic Population; Faculty; Fostering; Funding; Geographic Locations; Health; Healthcare; Hospitals; Industry; Infrastructure; Institution; Leadership; Measures; Medical center; Minority; Minority Groups; Minority Health Research; Minority Recruitment; Neurosciences; Participant; Patient Recruitments; Patients; Pediatric Hospitals; Pennsylvania; Performance; Physicians; Population; Prevention; Randomized; Recovery; Rehabilitation therapy; Research; Research Personnel; Resources; Rotation; Rural; Satellite Centers; Saturn; Site; Stroke; Stroke prevention; StrokeNet trials; Structure; Supervision; Support Groups; Telemedicine; Time; Training; Translational Research; United States National Institutes of Health; Universities; Update; Woman; career; career development; cerebrovascular; collaborative approach; experience; improved; innovation; insight; meetings; outreach; participant enrollment; participant retention; performance site; programs; racial population; recruit; retention rate; rural area; skills; stroke trials; suburb; success; trial planning; trustworthiness; underserved area; working group

Abstract Bridge funding is being requested to support our NIH StrokeNet Regional Coordinating Center (RCC) at the University of Pittsburgh (STN-UP) during the gap in funding that would otherwise occur between the current award (U24NS107216) ending on 7/31/2023 and the proposed new RCC award (RFA-NS-23-010) starting on 12/1/2023. Continued NIH support during this time will be essential for the STN-UP RCC to continue delivering regulatory efficiency, academic expertise, and oversight of high-quality performance in StrokeNet trials of stroke prevention, treatment, and recovery across our regional network. The leadership, supervision, management, and direct support provided by the RCC PI, Marcelo Rocha, Co-Is, Clif Callaway and Dana Cummings and RCC Manager, Jason Weimer is key to continued participation and enrollment into the ASPIRE, CAPTIVA, MOST, SATURN, SleepSMART, TRANSPORT2 and VERIFY trials. Core leadership will be instrumental to the timely start-up and multi-site initiation for the upcoming RHSPSODY-2, FOCAS and SISTER trials across research network partner sites, which will be occurring during the time of the potential gap in funding. FOCAS is the first NIH pediatric stroke trial that the STN-UP RCC will be participating in at the UPMC Children’s Hospital of Pittsburgh. Our RCC PI and Research Manager meet monthly with our regional satellite sites to help optimize trial start-up and efficient enrollment across the network. STN-UP will continue to build on its successful infrastructure and experience from previous funding cycles to support regulatory efficiency, academic expertise, and high-quality performance in StrokeNet trials focused on stroke prevention, treatment, and recovery. Our large STN-UP research network includes University of Pittsburgh Medical Center (UPMC) and St. Luke’s University Health hospitals, covering large urban, suburban, and rural areas of Pennsylvania, to support trial recruitment of stroke participants with diverse backgrounds. The specific aims of the STN-UP RCC during the the gap between awards is to: 1. To continue our collaborative and administrative structure to rapidly implement StrokeNet trials and enroll patients across a wide range of adult and pediatric populations. 2. Foster participation of physicians, patients, and patient support groups with equitable representation of women and minorities to meet or exceed accrual requirements.

摘要 正在申请桥梁资金，以支持我们的NIH StrokeNet区域协调中心（RCC）， 匹兹堡大学（STN-UP）在资金上的差距，否则将发生在目前的 合同（U24 NS 107216）于2023年7月31日结束，拟议的新RCC合同（RFA-NS-23-010）于 12/1/2023.在此期间，NIH的持续支持对于STN-UP RCC继续提供 监管效率、学术专业知识和对中风StrokeNet试验中高质量性能的监督 预防、治疗和康复。领导、监督、管理和 RCC PI、Marcelo罗查、Co-Is、Clif Callaway和Dana Cummings以及RCC提供的直接支持 经理，贾森韦默是关键，继续参与和登记到ASPIRE，CAPTIVA，MOST， SATURN、SleepSMART、TRANSPORT 2和VERIFY试验。核心领导将有助于及时 即将进行的RHSPSODY-2、FOCAS和SISTER试验的启动和多中心启动 网络伙伴网站，这将在资金可能出现缺口的时候发生。FOCAS是第一个 STN-UP RCC将参加的NIH儿科中风试验在UPMC儿童医院进行， 匹兹堡我们的RCC PI和研究经理每月与我们的区域卫星站点会面， 试验启动和整个网络的高效入组。STN-UP将继续在其成功的基础上 基础设施和以往资金周期的经验，以支持监管效率，学术专长， 在中风预防、治疗和康复的StrokeNet试验中的高质量表现。我们 大型STN-UP研究网络包括匹兹堡大学医学中心（UPMC）和圣卢克大学 大学健康医院，覆盖宾夕法尼亚州的大城市、郊区和农村地区，以支持试验 招募具有不同背景的中风参与者。在2010年期间，科技促进发展协调委员会的具体目标是： 奖项之间的差距是：1。继续我们的合作和行政结构，以迅速实施 StrokeNet试验并招募了广泛的成人和儿童人群的患者。2.促进参与 医生，病人和病人支持团体，妇女和少数民族的公平代表， 达到或超过应计要求。