Stroke Trials Network-Regional Coordinating Center University of Pittsburgh (STN-UP)

中风试验网络-匹兹堡大学区域协调中心 (STN-UP)

• 批准号: 10847050
• 负责人: MARCELO ROCHA
• 金额: $ 7.95万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2023-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10847050
• 关键词: Acute; Admission activity; Adopted; Adult; Advisory Committees; Ambulatory Care Facilities; Area; Award; Catchment Area; Childhood; Childhood stroke; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Clinical Trials Network; Collaborations; Communities; Community Hospitals; Consultations; Data Coordinating Center; Discipline; Education; Emergency Care; Enrollment; Ensure; Equity; Ethnic Population; Faculty; Fostering; Funding; Geographic Locations; Health; Healthcare; Hospitals; Industry; Infrastructure; Institution; Leadership; Measures; Medical center; Minority; Minority Groups; Minority Health Research; Minority Recruitment; Neurosciences; Participant; Patient Recruitments; Patients; Pediatric Hospitals; Pennsylvania; Performance; Physicians; Population; Prevention; Randomized; Recovery; Rehabilitation therapy; Research; Research Personnel; Resources; Rotation; Rural; Satellite Centers; Saturn; Site; Stroke; Stroke prevention; StrokeNet trials; Structure; Supervision; Support Groups; Telemedicine; Time; Training; Translational Research; United States National Institutes of Health; Universities; Update; Woman; career; career development; cerebrovascular; collaborative approach; experience; improved; innovation; insight; meetings; outreach; participant enrollment; participant retention; performance site; programs; racial population; recruit; retention rate; rural area; skills; stroke trials; suburb; success; trial planning; trustworthiness; underserved area; working group

Abstract Bridge funding is being requested to support our NIH StrokeNet Regional Coordinating Center (RCC) at the University of Pittsburgh (STN-UP) during the gap in funding that would otherwise occur between the current award (U24NS107216) ending on 7/31/2023 and the proposed new RCC award (RFA-NS-23-010) starting on 12/1/2023. Continued NIH support during this time will be essential for the STN-UP RCC to continue delivering regulatory efficiency, academic expertise, and oversight of high-quality performance in StrokeNet trials of stroke prevention, treatment, and recovery across our regional network. The leadership, supervision, management, and direct support provided by the RCC PI, Marcelo Rocha, Co-Is, Clif Callaway and Dana Cummings and RCC Manager, Jason Weimer is key to continued participation and enrollment into the ASPIRE, CAPTIVA, MOST, SATURN, SleepSMART, TRANSPORT2 and VERIFY trials. Core leadership will be instrumental to the timely start-up and multi-site initiation for the upcoming RHSPSODY-2, FOCAS and SISTER trials across research network partner sites, which will be occurring during the time of the potential gap in funding. FOCAS is the first NIH pediatric stroke trial that the STN-UP RCC will be participating in at the UPMC Children’s Hospital of Pittsburgh. Our RCC PI and Research Manager meet monthly with our regional satellite sites to help optimize trial start-up and efficient enrollment across the network. STN-UP will continue to build on its successful infrastructure and experience from previous funding cycles to support regulatory efficiency, academic expertise, and high-quality performance in StrokeNet trials focused on stroke prevention, treatment, and recovery. Our large STN-UP research network includes University of Pittsburgh Medical Center (UPMC) and St. Luke’s University Health hospitals, covering large urban, suburban, and rural areas of Pennsylvania, to support trial recruitment of stroke participants with diverse backgrounds. The specific aims of the STN-UP RCC during the the gap between awards is to: 1. To continue our collaborative and administrative structure to rapidly implement StrokeNet trials and enroll patients across a wide range of adult and pediatric populations. 2. Foster participation of physicians, patients, and patient support groups with equitable representation of women and minorities to meet or exceed accrual requirements.

抽象的 正在申请过桥资金来支持我们的 NIH StrokeNet 区域协调中心 (RCC) 匹兹堡大学（STN-UP）在资金缺口期间，否则当前的 奖项 (U24NS107216) 于 2023 年 7 月 31 日结束，拟议的新 RCC 奖项 (RFA-NS-23-010) 于 2023 年 7 月 31 日结束 2023 年 12 月 1 日。在此期间，NIH 的持续支持对于 STN-UP RCC 继续提供服务至关重要 StrokeNet 卒中试验中的监管效率、学术专业知识和高质量表现的监督 我们整个区域网络的预防、治疗和康复。领导、监督、管理和 由 RCC PI、Marcelo Rocha、Co-Is、Clif Callaway 和 Dana Cummings 以及 RCC 提供的直接支持 经理 Jason Weimer 是继续参与和注册 ASPIRE、CAPTIVA、MOST、 SATURN、SleepSMART、TRANSPORT2 和 VERIFY 试验。核心领导层将有助于及时 即将进行的 RHSPSODY-2、FOCAS 和 SISTER 跨研究试验的启动和多站点启动 网络合作伙伴网站，这将在资金存在潜在缺口时发生。 FOCAS是第一个 STN-UP RCC 将在 UPMC 儿童医院参与 NIH 儿童中风试验 匹兹堡。我们的 RCC PI 和研究经理每月与我们的区域卫星站点会面，以帮助优化 试启动和全网络高效注册。 STN-UP 将在其成功的基础上继续发展 基础设施和以前融资周期的经验，以支持监管效率、学术专业知识、 以及专注于中风预防、治疗和康复的 StrokeNet 试验的高质量表现。我们的 大型 STN-UP 研究网络包括匹兹堡大学医学中心 (UPMC) 和圣卢克大学 覆盖宾夕法尼亚州大城市、郊区和农村地区的大学健康医院支持试验 招募具有不同背景的中风参与者。 STN-UP RCC 期间的具体目标 奖项之间的差距在于： 1. 继续我们的协作和管理结构，以快速实施 StrokeNet 进行试验并招募广泛的成人和儿童人群的患者。 2. 促进参与 由医生、患者和患者支持团体组成，其中女性和少数族裔具有公平的代表性 达到或超过应计要求。