DEVELOPMENT OF A NOVEL THERAPEUTIC FOR MELIOIDOSIS
DEVELOPMENT OF A NOVEL THERAPEUTIC FOR MELIOIDOSIS
批准号:
10888122
负责人:
M.R.K. (DICKON) ALLEY
金额:
$65.1万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
未结题
起止时间:
2022-09-20 至 2025-04-14
关键词:
Advanced DevelopmentAntibiotic ResistanceBurkholderia pseudomalleiCategoriesChemistryClinicalDevelopmentEmerging Communicable DiseasesMelioidosisNational Institute of Allergy and Infectious DiseasePathway interactionsefficacy evaluationmanufacturenovel therapeuticspre-clinicalpriority pathogenproduct developmentresearch and developmentsafety assessmenttherapeutic candidatetherapeutic development
中文摘要
支持NIAID A、B和C类优先病原体或新发传染病的有前景候选治疗药物的高级开发。支持的研发活动将使候选治疗产品通过产品开发途径取得进展,包括临床前和IND使能开发活动、化学优化/开发、GMP生产以及临床安全性和有效性评估。
英文摘要
To support the advanced development of a promising candidate therapeutic for NIAID Category A, B, and C Priority Pathogens or emerging infectious diseases. The research and development activities to be supported will allow the candidate therapeutic product to progress through the product development pathway, and include preclinical and IND enabling development activities, chemistry optimization/development, GMP manufacturing, and clinical safety and efficacy assessment.
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DEVELOPMENT OF A NOVEL THERAPEUTIC FOR MELIOIDOSIS
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批准号:10710593
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项目类别:
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资助金额:$430.64万
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财政年份:2022
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负责人:M.R.K. (DICKON) ALLEY
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依托单位:
海外基金