Neural coding and perception of learned vocalizations

神经编码和习得发声的感知

• 批准号: 10862036
• 负责人: Sarah M Woolley
• 金额: $ 59.04万
• 依托单位: COLUMBIA UNIV NEW YORK MORNINGSIDE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10862036
• 关键词: Acoustics; Acute; Adult; Animal Model; Auditory; Auditory Perception; Auditory area; Back; Behavior; Behavioral; Biological Assay; Birds; Brain; Child; Chronic; Code; Communication; Data Analyses; Development; Developmental Delay Disorders; Diagnosis; Disease; Electrophysiology (science); Frequencies; Genetic; Goals; Grant; Hearing; Human; Infant; Knowledge; Language; Language Development; Learning; Life; Measures; Mission; Modeling; Neurons; Operant Conditioning; Otitis Media; Pathway interactions; Pattern; Perception; Phonetics; Presbycusis; Prevention; Process; Production; Property; Research; Resolution; Shapes; Songbirds; Speech; Speech Perception; Speech Sound; Structure; Testing; Time; Training; United States National Institutes of Health; Voice; Work; auditory processing; autism spectrum disorder; communication behavior; comparative; design; early experience; experience; experimental study; flexibility; genetic architecture; improved; insight; instrument; learned behavior; neural; neuromechanism; neurophysiology; novel; preference; response; skills; sound; syntax; tutoring; vocal learning; vocalization; zebra finch

Project Summary Hearing and voice are the principal instruments of human communication. Early auditory experience of speech organizes perception around native language(s) sounds for life. This early specialization of auditory processing facilitates language development and predicts adult proficiency. While the acoustic features of speech sounds differ across languages, the temporal structure of speech is constrained and hierarchical in all languages. An important goal in the pursuit to understand how we acquire and use speech and what goes wrong when we can’t use speech is determining how auditory encoding on multiple time scales relates to vocal communication structure, vocal learning and perception. We propose to integrate manipulations in vocal learning with precise measures of cortical auditory encoding and perceptual skills to determine the encoding properties that promote flexible learning of syllable structure and constrain the temporal organization of syllables (syntax), in songbirds. The proposed experiments will identify neural mechanisms whereby vocal communication behavior is both learned and genetically-determined. The significance of the proposed research to the NIH mission is three-fold. First, this work will identify auditory encoding capacities that support vocal learning. Second, the work will test the limits of vocal learning to identify neural and perceptual mechanisms that impose structure on the acoustic features and temporal organization of vocal communication behavior. Third, our results will provide insights into how manipulations of experience and training can improve the prevention, diagnosis and treatment of speech deficits such as those observed in children with auditory spectrum disorders.

项目概要 听觉和声音是人类交流的主要工具。言语的早期听觉体验 终生围绕母语声音组织感知。这种听觉处理的早期专业化 促进语言发展并预测成人熟练程度。虽然语音的声学特征 不同语言之间存在差异，语音的时间结构在所有语言中都是受到限制和分层的。一个 追求理解我们如何获取和使用言语以及当我们无法获取和使用言语时会出现什么问题的重要目标 使用语音决定了多个时间尺度上的听觉编码与声音交流的关系 结构、声音学习和感知。我们建议将声乐学习中的操作与精确的 皮层听觉编码和感知技能的测量，以确定促进的编码特性 在鸣禽中灵活学习音节结构并限制音节（语法）的时间组织。 拟议的实验将确定声音交流行为的神经机制 后天习得并由基因决定。拟议的研究对 NIH 使命具有三重意义。 首先，这项工作将确定支持声音学习的听觉编码能力。二、工作将检验 声乐学习的局限性，无法识别对声学施加结构的神经和感知机制 声音交流行为的特征和时间组织。第三，我们的研究结果将提供以下见解： 经验和训练的运用如何改善言语的预防、诊断和治疗 缺陷，例如在患有听觉频谱障碍的儿童中观察到的缺陷。

项目成果

Auditory sensitivity and vocal acoustics in five species of estrildid songbirds.

五种梅花鸟的听觉敏感性和声音声学。

• DOI: 10.1016/j.anbehav.2022.11.002
• 发表时间: 2023
• 期刊: Animal behaviour
• 影响因子: 2.5
• 作者: Yeh,Yow-Tyng;Rivera,Moises;Woolley,SarahMN
• 通讯作者: Woolley,SarahMN

Sex differences and endocrine regulation of auditory-evoked, neural responses in African clawed frogs (Xenopus).

• DOI: 10.1007/s00359-015-1049-9
• 发表时间: 2016-01
• 期刊: Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology
• 作者: Hall IC;Woolley SM;Kwong-Brown U;Kelley DB
• 通讯作者: Kelley DB