Administrative Supplements for the NCI P30 Cancer Center Support Grants for Multi-Channel Communication Campaigns for Improvements in Cancer Education and Outcomes (MICEO) in Underserved Populations

NCI P30 癌症中心行政补充，支持多渠道沟通活动，以改善服务不足人群的癌症教育和结果 (MICEO)

• 批准号: 10891877
• 负责人: Boris Pasche
• 金额: $ 20万
• 依托单位: WAYNE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-12-01 至 2025-11-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10891877
• 关键词: Academy; Adherence; Administrative Supplement; Area; Black race; Breast Cancer Detection; Businesses; COVID-19 pandemic; Cancer Center Support Grant; Cancer Control; Catchment Area; Censuses; Cities; Collaborations; Communication; Communities; Development; Diagnosis; Future; General Population; Goals; Health; Institution; Intervention; Knowledge; Malignant Neoplasms; Mammographic screening; Mammography; Marketing; Media Campaign; Medically Underserved Area; Michigan; Outcome; Population; Poverty; Risk; Screening for cancer; Social Network; Training; Underserved Population; United States Health Resources and Services Administration; Woman; Work; aged; black women; cancer education; cancer prevention; community building; improved; literacy; malignant breast neoplasm; member; metropolitan; mortality; pandemic disease; pre-pandemic; programs; psychoeducation; psychoeducational; screening; social media

Abstract The catchment area of Karmanos Cancer Institute (KCI) includes Southeast Michigan and the city of Detroit. According to the 2022 U.S. Census, 78% of Detroiters identify as Black, 32% live in poverty compared to 13% in the state of Michigan, and the majority of census tracts in the city of Detroit are medically underserved areas (MUAs) based on HRSA definitions. Engaging this population in cancer prevention and control efforts is essential. In the proposed work, we will address Track 2 with a focus on the General Population (30+ years) and breast cancer screening. Our preliminary work suggests some delay in mammography screening due to the COVID-19 pandemic, consistent with other work indicating missed or delayed cancer screenings in the first year of the pandemic 1 2 and lower than pre-pandemic screening levels in the second year 3, raising concerns about a future risk in late-stage diagnoses. This is especially concerning given the breast cancer mortality rates of 34.3 per 100,000 among Black women in Detroit compared to 21.3 per 100,00 among White women in the KCI catchment area. Breast cancer screening promotion is consistent with an emerging KCI OCHECE initiative: Karmanos Academy, a program with the primary goal of building community capacity for improving cancer prevention and control throughout the KCI catchment area. Through Karmanos Academy, community members will be trained as lay health advisors (LHAs) to deliver relevant interventions within local organizations and institutions as well as their own social networks. The proposed work has three aims: Aim 1: Adapt an existing LHA-led psychoeducational program to increase mammography adherence among Black women in the metropolitan Detroit area in collaboration with community stakeholders; Aim 2: Collaborate with existing KCI OCHECE community partners to enlist and train community members as LHAs who will deliver the adapted psychoeducational program; Aim 3: Partner with KCI's Marketing and Business Development Department to develop and implement a social media toolkit to promote mammography adherence among Black women in the metropolitan Detroit area. We will create a video-based adaptation of the Real Talk intervention to increase mammography adherence among Black women aged 40 years and older. This video will be an integral part of LHA-led sessions on this topic, session coordinated in tandem with a social media campaign. Ultimately, the proposed work will improve cancer literacy and breast cancer knowledge among Black women in metro Detroit through strategic use of multiple communication channels.

摘要 Karmanos癌症研究所（KCI）的集水区包括密歇根州东南部和 底特律根据2022年美国人口普查，78%的底特律人认为自己是黑人，32%的人生活在贫困中， 在密歇根州，这一比例为13%，底特律市的大多数人口普查区都是医疗区。 根据HRSA定义的服务不足地区（MUAs）。让这一人群参与癌症预防， 控制工作至关重要。在拟议的工作中，我们将处理第二轨道，重点是一般性问题， 30岁以上人群和乳腺癌筛查。我们的初步调查显示 由于COVID-19大流行，乳房X光检查筛查与其他工作一致，表明错过或 大流行第一年的癌症筛查延迟1 2，筛查水平低于大流行前 在第二年3，提高了对后期诊断的未来风险的担忧。这尤其令人担忧 考虑到底特律黑人妇女的乳腺癌死亡率为每10万人34.3人， KCI集水区的白色妇女中每100，00人中就有1人死亡。乳腺癌筛查推广一致 随着一个新兴的KCI OKEE倡议：Karmanos学院，一个计划的主要目标是建立 提高整个KCI集水区的癌症预防和控制的社区能力。通过 Karmanos学院，社区成员将接受非专业健康顾问（LHA）培训，以提供相关服务 在地方组织和机构以及他们自己的社交网络内进行干预。拟议 工作有三个目标：目标1：调整现有的LHA领导的心理教育计划，以增加 底特律大都市地区黑人妇女的乳房X光检查依从性， 社区利益相关者;目标2：与现有的KCI OKEE社区合作伙伴合作， 培训社区成员作为LHA，他们将提供经过调整的心理教育计划;目标3：合作伙伴 与KCI的市场营销和业务发展部合作，开发和实施社交媒体工具包 在底特律大都市地区的黑人妇女中促进乳房X光检查的依从性。我们将创建一个 基于视频的真实的谈话干预的适应性调整，以增加黑人的乳腺X线摄影依从性 40岁及以上的妇女。该视频将成为LHA主导的关于此主题的会议的组成部分， 与社交媒体活动协调一致。最终，这项工作将改善癌症 通过战略性地使用多种工具， 沟通渠道。

项目成果

Scutellaria extract and wogonin inhibit tumor-mediated induction of T(reg) cells via inhibition of TGF-β1 activity.

• DOI: 10.1007/s00262-011-1130-3
• 发表时间: 2012-05
• 期刊: CANCER IMMUNOLOGY IMMUNOTHERAPY
• 影响因子: 5.8
• 作者: Dandawate, Sagar;Williams, Linford;Joshee, Nirmal;Rimando, Agnes M.;Mittal, Sandeep;Thakur, Archana;Lum, Lawrence G.;Parajuli, Prahlad
• 通讯作者: Parajuli, Prahlad

Dairy, calcium, vitamin D and ovarian cancer risk in African-American women.

非裔美国女性的乳制品、钙、维生素 D 和卵巢癌风险。

• DOI: 10.1038/bjc.2016.289
• 发表时间: 2016-10-25
• 期刊: BRITISH JOURNAL OF CANCER
• 影响因子: 8.8
• 作者: Qin, Bo;Moorman, Patricia G.;Alberg, Anthony J.;Barnholtz-Sloan, Jill S.;Bondy, Melissa;Cote, Michele L.;Funkhouser, Ellen;Peters, Edward S.;Schwartz, Ann G.;Terry, Paul;Schildkraut, Joellen M.;Bandera, Elisa V.
• 通讯作者: Bandera, Elisa V.

Incidence and survival for oropharynx and non-oropharynx head and neck cancers among veterans living with HIV.

• DOI: 10.1002/cam4.3539
• 发表时间: 2020-12
• 期刊: Cancer medicine
• 影响因子: 4
• 作者: Mazul AL;Hartman C;Kramer J;White DL;Royse K;Raychaudhury S;Sandulache V;Ahmed ST;Richardson P;Sikora AG;Chiao E
• 通讯作者: Chiao E

Positive associations between galectin-3 and PSA levels in prostate cancer patients: a prospective clinical study-I.

• DOI: 10.18632/oncotarget.12619
• 发表时间: 2016-12-13
• 期刊: Oncotarget
• 作者: Nakajima K;Heilbrun LK;Hogan V;Smith D;Heath E;Raz A
• 通讯作者: Raz A

CARP-1 functional mimetics: a novel class of small molecule inhibitors of medulloblastoma cell growth.

• DOI: 10.1371/journal.pone.0066733
• 发表时间: 2013
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Ashour AE;Jamal S;Cheryan VT;Muthu M;Zoheir KM;Alafeefy AM;Abd-Allah AR;Levi E;Tarca AL;Polin LA;Rishi AK
• 通讯作者: Rishi AK