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The Mid-Atlantic Center for Cardiometabolic Health Equity (MACCHE)

大西洋中部心脏代谢健康公平中心 (MACCHE)

基本信息

批准号：
10892551
负责人：
LISA A COOPER
金额：
$ 97.25万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-24 至 2026-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10892551
关键词：
Address Adult Area Baltimore Birth Black race Cardiometabolic Disease Cardiovascular system Chronic Chronic Disease Chronic Kidney Failure Clinical Cluster randomized trial Communities Community Health Aides Complex DASH diet Development Diabetes Mellitus Diet Disease Management Disparity Disparity population Economics Ethnic Origin Fibrosis Food Goals Health Health Food Health Policy Heart Heart Injuries Heart failure High Risk Woman Home Blood Pressure Monitoring Home visitation Hypertension Intervention Latinx Leadership Life Life Cycle Stages Link Maryland Medicine Mentors Morbidity - disease rate Myocardial dysfunction Non-Insulin-Dependent Diabetes Mellitus Obesity Outcome Outcomes Research Ownership Patient-Focused Outcomes Persons Pharmacists Phase Pilot Projects Policies Population Postpartum Period Postpartum Women Pregnancy Pregnant Women Problem Solving Provider Public Health Practice Quality of life Race Recommendation Recovery Research Research Personnel Research Project Grants Risk Factors Science Services Sodium Chloride Structure Testing Training Translating Translations United States blood pressure control blood pressure reduction cardiometabolic risk cardiometabolism cardiorespiratory fitness community based participatory research community center community engaged research community engagement compare effectiveness comparison intervention design dietary disease disparity disorder prevention effectiveness evaluation effectiveness testing ethnic disparity evidence base fitness food desert fruits and vegetables geographic disparity health disparity health equity high risk improved innovation low socioeconomic status mortality postpartum health postpartum weight programs racial disparity randomized trial social disparities socioeconomic disparity stress management stress reduction team-based care telemonitoring treatment as usual

项目摘要

OVERALL PROJECT SUMMARY The overarching goal of the Mid-Atlantic Center for Cardiometabolic Health Equity (MACCHE) is to test the effectiveness of comprehensive, integrated, and multi-level evidence-based strategies for improving cardiometabolic health outcomes among socially disadvantaged populations in Maryland. The MACCHE will include 5 separate, but related research projects addressing disparities in cardiometabolic disease; 3 integrated cores (Administrative, Investigator Development, and Community Engagement); an Executive Committee; and a Community Advisory Board. The first 3 projects are currently underway and include: Project 1 (Healthy for Two), a randomized trial comparing the effectiveness of an evidence-based pregnancy/postpartum health coaching/home visiting intervention to usual home visiting services in reducing postpartum weight retention among Black and Latinx birthing people at high risk for cardiometabolic health disparities; Project 2 (UNLOAD-Heart Failure) is a randomized trial examining the effectiveness of a multi-level intervention of problem-solving training, community health worker (CHW) support and partnership with community facilities for enhancing cardiorespiratory fitness in adults with low socioeconomic status, diabetes, obesity and asymptomatic cardiac dysfunction; and Project 3 (LINKED-HEARTS) is a cluster-randomized trial testing the effectiveness of a multi-level intervention linking self-monitored blood pressure (BP) with telemonitoring, team-based care with pharmacists and CHWs, and provider-level interventions compared to enhanced usual care, for improving BP control among socially disadvantaged adults with uncontrolled hypertension plus diabetes or chronic kidney disease. The 2 additional proposed studies include: Healthy for Two-Hearts which builds upon Healthy For Two, to address racial and ethnic disparities in hypertension in postpartum birthing people, with an emphasis on two effective strategies for blood pressure reduction: low salt/high fruit and vegetable diet (including food delivery) and stress management; and DASH-Life which will pilot a Food-is-Medicine intervention for adults with hypertension and type 2 diabetes residing in Healthy Food Priority Areas in Baltimore (`food deserts')—a population at high risk for adverse cardiometabolic health outcomes. The MACCHE will advance the science of cardiometabolic disease disparities and facilitate its translation into clinical and public health practice and policy.

整体项目摘要中大西洋心脏代谢健康公平中心（MACHE）的首要目标是测试全面、综合和多层次循证战略的有效性，马里兰州社会弱势人群的心脏代谢健康结果。MACHE将包括5个独立但相关研究项目，以解决心脏代谢疾病方面的差异; 3 综合核心（行政、研究者发展和社区参与）; 委员会;和一个社区咨询委员会。目前正在进行的前三个项目包括： 1（两个人的健康），一项随机试验，比较了基于证据的怀孕/产后健康辅导/家访干预，以减少心脏代谢健康高危黑人和拉丁裔分娩人群产后体重保持情况差异;项目2（卸载-心力衰竭）是一项随机试验，检查多水平解决问题培训、社区卫生工作者支持和与社区设施，用于提高社会经济地位低，糖尿病，肥胖和无症状心功能不全;项目3（LINKED-HEARTS）是一项随机分组试验测试将自我监测血压（BP）与远程监护，与药剂师和CHW的团队护理以及提供者级别的干预相比，加强常规护理，以改善社会弱势成人的血压控制，高血压合并糖尿病或慢性肾病。另外2项拟议研究包括：建立在两个人健康基础上的两颗心，以解决高血压的种族和民族差异，产后分娩的人，重点是两个有效的降低血压的策略：低盐/高水果和蔬菜饮食（包括食品交付）和压力管理;和DASH-Life，为居住在健康食品区的高血压和2型糖尿病成年人试行食品即药物干预巴尔的摩的优先领域（“食物沙漠”）-心脏代谢健康不良的高风险人群结果。MACCHE将推进心脏代谢疾病差异的科学，并促进其转化为临床和公共卫生实践和政策。