Mechanisms of ataxia in spinocerebellar ataxia type 1 transgenic mice

大脑协调部分（小脑）的退化导致共济失调。有很多类型，但很少能治愈。大多数，约3000名澳大利亚人，是进行性的，只能通过物理治疗来帮助。我们正在通过分析遗传性共济失调小鼠小脑中的化学递质，寻找一种药物来改善共济失调的症状。如果我们发现不平衡，我们将尝试适当的药物来纠正这种情况并减轻共济失调。

Degeneration of the coordination part of the brain (cerebellum) causes ATAXIA. There are many types, but few can be cured. The majority, affecting ~ 3,000 Australians, are progressive, and can only be helped by physical therapies. We are searching for a drug to improve the SYMPTOMS of ataxia, by analysing the chemical transmitters in the cerebellum in genetically ataxic mice. If we find an imbalance, we will trial appropriate drugs to try to correct this and lessen ataxia.