Mechanisms contributing to long-term neuronal loss after hypoxia-ischemia in the premature neonate brain.

出生时大脑缺氧（缺氧）和供血不足（缺血）会导致脑损伤，并持续到成年。财政、教育和医疗资源的负担是巨大的。我们将进一步了解缺氧缺血后大脑的哪些部位受损，以及导致持续脑损伤的机制。这对设计治疗方法和为新生儿提供健康的生命开端至关重要。

A lack of oxygen (hypoxia) and blood flow to the brain (ischemia) around the time of birth can cause brain injury that perists into adulthood. The burdens on financial, educational and healthcare resources are enormous. We will improve our understanding of what parts of the brain are injured and the mechanisms contributing to on-going brain injury after hypoxia-ischemia.This is important to devise treatments and to provide a healthy start to life for neonates.