Wireless Movement Disorder Monitor

描述(由申请人提供)：目标是设计、建造和临床评估一种用于监测和记录运动障碍的无线设备。具体地说，该设备将用于评估帕金森氏症治疗的疗效。帕金森氏症导致残疾的三个主要症状包括震颤、运动迟缓和僵硬。目前的治疗方法，如药物干预和脑深部刺激，侧重于缓解这些症状，以提高生活质量。客观地量化这些症状将有助于评估这些干预措施的效果。该项目将整合硬件和开发软件算法，以分析、量化并向临床医生提供定量数据。量化数据将与目前的评估标准--联合帕金森氏病评定量表--相关。该设备将包括临床医生和研究界面。这种无线设备可以在家中或在步态等活动期间提供帕金森氏症的实时监测。最终的设备将允许在家中对帕金森患者进行研究。在家中监测帕金森的症状将使医生能够捕捉到在办公室就诊时看不到的症状的复杂波动模式。该设备将把在患者家中收集的数据下载到医生办公室的计算机上。这将允许医生适当地改变治疗方案。

DESCRIPTION (provided by applicant): The objective is to design, build, and clinically assess a wireless device for monitoring and recording movement disorders. Specifically, the device will be developed for evaluating the efficacy of treatments for Parkinson's disease. Three major symptoms of Parkinson's disease that lead to disability include tremor, bradykinesia, and rigidity. Current treatments such as pharmaceutical interventions and deep brain stimulation focus on alleviating these symptoms to improve quality of life. Objectively quantifying these symptoms will aid in evaluating the efficacy of these interventions. The project will integrate hardware and develop software algorithms to analyze, quantify, and present quantitative data to clinicians. The quantitative data will be related to the current standard for evaluation, the United Parkinson's Disease Rating Scale. The device will include clinician and research interfaces. The wireless device could provide real-time monitoring of Parkinson's at home or during activities such as gait. The final device will allow at-home studies of Parkinson's patients. Monitoring Parkinson's symptoms at home would allow physicians to capture complex fluctuation patterns of the symptoms not seen during an office visit. The device would download data collect at a patient's home to a computer at the physician's office. This will allow physicians to change treatment protocols appropriately.