Hot Flash Ambulatory Monitor

潮热动态监测仪

• 批准号: 7014812
• 负责人: MATTHEW D. TARLER
• 金额: $ 25万
• 依托单位: CLEVELAND MEDICAL DEVICES, INC.
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-30 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7014812
• 关键词: biomedical equipment development; biosensor device; body temperature; clinical research; cost effectiveness; electrodes; female; hot flash; human subject; humidity; miniature biomedical equipment; monitoring device; portable biomedical equipment

DESCRIPTION (provided by applicant): Hot flashes range from very annoying distraction to debilitating condition for the 75% or more post- menopausal women that experience them. Although many treatment options have been proposed, most of these treatments have significant risks or little to no scientific proof of effectiveness. Skin conductance has been identified as the single best objective detection of hot flashes. The proposed work will produce an improved clinical tool for detection and recording of hot flashes. This new device will be smaller and more versatile than the existing technology and most importantly virtually invisible to a bystander when being worn. The proposed device will detect and record hot-flash occurrences using skin conductance and also record user perceived hot flashes through a user activated button. Additional sensors that will work in conjunction with skin conductance measurement will further improve the reliability of hot flash measurement. This program will test each of these additional sensors for their efficacy and cost effectiveness in improving sensitivity or positive predictivity of hot flash detection, or the addition of detecting relative hot flash intensity and duration. At the end of this program, a new tool will be available to researchers for objectively validating hot flash treatment options.

描述（由申请人提供）：潮热的范围从非常恼人的分心到衰弱的条件，为75%或更多的绝经后妇女的经验。虽然已经提出了许多治疗方案，但大多数治疗方法都有显著的风险，或者几乎没有有效性的科学证据。皮肤电导已被确定为潮热的单一最佳客观检测。拟议的工作将产生一个改进的临床工具，用于检测和记录潮热。这种新设备将比现有技术更小，更通用，最重要的是，当佩戴时，旁观者几乎看不见。申报器械将使用皮肤电导检测并记录潮热事件，并通过用户激活按钮记录用户感知的潮热。将与皮肤电导测量结合工作的附加传感器将进一步提高潮热测量的可靠性。该计划将测试这些附加传感器中的每一个在提高热闪检测的灵敏度或阳性预测性或增加检测相对热闪强度和持续时间方面的功效和成本效益。在该计划结束时，研究人员将获得一种新的工具，用于客观地验证潮热治疗方案。