PREVALENCE AND IMPACT OF GLAUCOMA AMONG THE VERY ELDERLY

描述：(申请人摘要)青光眼患病率随年龄增长而增加 这一比例在白人中高达5%，在70多岁的黑人中高达10%。 以前的基于人口的调查对患病率的估计很差。 75岁以上人群中的青光眼。拟议的研究将获得 对青光眼患病率的可靠估计是增长最快的 美国人口的一部分，个人年龄在75岁及以上。 这项计划中的研究将补充已经安排的对大型 将于2001年6月举行的多种族老年人队列 马里兰州东部。索尔兹伯里眼睛评估项目(见)，于#年启动 是一项正在进行的基于人群的队列研究，研究对象为2520人 现在已经74岁到93岁。研究参与者还没有被系统地 评估是否患有青光眼。 除了确定最年长老年人的青光眼负担外， 拟议的研究将评估视野丧失对功能的影响。看见 调查人员不仅在收集患者报告的对他们的 进行日常生活活动的能力，他们也在管理 基于性能的身体机能测试。其中包括平衡测试， 日常任务的机动性和执行情况。目前的建议，通过改进 青光眼视野检查和眼科检查的质量 专家们不仅将确定青光眼病例，还将确定 不同程度青光眼与非青光眼对视野的影响 功能损失。具体地说，目前的研究将探索 患者行动不便的视野丧失、患者报告的跌倒和对 下降，以及日常生活活动的限制。广博的数据 收集有关身体和认知并存的信息将允许 分析中的调整，以便视野损失的影响可以 独立于这些因素进行评估。最后，两国之间的互动 合并症(包括认知障碍)和视野丧失 探索过了。

DESCRIPTION: (Applicant's Abstract) Glaucoma prevalence increases with age with rates as high as 5% among whites and 10% among blacks in their seventies. Previous population-based surveys give poor estimates of the prevalence of glaucoma among those over 75 years of age. The proposed research will obtain solid estimates of glaucoma prevalence rates among the most rapidly increasing segment of the United States population, individuals 75 years of age and older. The planned research will supplement an already scheduled evaluation of a large multiracial cohort of older individuals that will take place in June 2001 in Eastern Maryland. The Salisbury Eye Evaluation project (SEE), initiated in August 1992, is an ongoing population-based cohort study of 2,520 people who are now 74 to 93 years old. Study participants have not been systematically evaluated for glaucoma. In addition to determining the burden of glaucoma among the oldest old, the proposed study will assess the impact of visual field loss on function. SEE investigators are not only collecting patient-reported assessments of their ability to perform activities of daily living, they are also administering performance-based tests of physical function. These include tests of balance, mobility and performance of routine tasks. The current proposal, by improving the quality of visual field testing and providing eye examinations by glaucoma specialists will not only identify glaucoma cases, but will also determine the impact of varying degrees of glaucomatous and non-glaucomatous visual field loss on function. Specifically, the current research will explore the effect of visual field loss on patient mobility, patient-reported falls and fear of falling, and limitations in activities of daily living. The extensive data being collected on physical and cognitive comorbidities will allow for adjustments in the analysis so that the impact of visual field loss can be assessed independently from these factors. Finally, the interactions between comorbidities (including cognitive deficits) and visual field loss will be explored.