Mechanisms underlying impaired neuroplasticity in adolescents born preterm

早产会导致学习和运动障碍。我们有初步证据表明，这些缺陷会持续到青春期，这是由于大脑重组（可塑性）的能力有限。我们将确认和描述早产青少年的学习/运动缺陷，并探讨可塑性受损是否与此有关。该项目将为开发新的干预措施提供重要信息，以帮助早产儿童取得最佳结果。

Preterm birth can lead to learning and motor deficits. We have preliminary evidence that these deficits last into adolescence and are due to a limited ability of the brain to reorganise (plasticity). We will confirm and characterise the learning/motor deficits seen in adolescents born preterm and explore if impaired plasticity is responsible. This project will provide vital information for the development of novel interventions to help children born prematurely to achieve best outcomes.