Mechanisms underlying impaired neuroplasticity in adolescents born preterm

早产青少年神经可塑性受损的机制

• 批准号: nhmrc : 1065016
• 负责人: Dr Julia Pitcher
• 金额: $ 35.24万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/mechanisms-underlying-impaired-born-preterm/455147
• 关键词: Mechanisms; underlying; impaired; neuroplasticity; adolescents

Preterm birth can lead to learning and motor deficits. We have preliminary evidence that these deficits last into adolescence and are due to a limited ability of the brain to reorganise (plasticity). We will confirm and characterise the learning/motor deficits seen in adolescents born preterm and explore if impaired plasticity is responsible. This project will provide vital information for the development of novel interventions to help children born prematurely to achieve best outcomes.

早产可能会导致学习和运动障碍。我们有初步证据表明，这些缺陷会持续到青春期，并归因于大脑重组(可塑性)的能力有限。我们将确认和描述早产青少年的学习/运动缺陷，并探索可塑性受损是否负有责任。该项目将为制定新的干预措施提供重要信息，以帮助早产儿童实现最佳结局。