CLINICAL RESEARCH COOPERATIVE

临床研究合作社

• 批准号: 6941410
• 负责人: GEORGE Edward WOODY
• 金额: $ 150万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-30 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6941410
• 关键词: behavior therapy; behavioral /social science research tag; buprenorphine; clinical research; clinical trials; cocaine; community mental health services; cooperative study; drug abuse chemotherapy; drug abuse therapy; health care cost /financing; health care service availability; health services research tag; human subject; naloxone; psychosocial service; training

As clinical trial researchers and treatment providers since 1974, we believe that the major need within the field of addiction is for a working partnership between leaders in the research and in the treatment provider community. This partnership should elevate the standards of both treatment and research in this field. To this end we have Philadelphia metropolitan statistical area as part of the NIDA Clinical Trials Network. We have recruited and cultivated collaborative relationships with seven of the very best organizations representing 60 treatment programs from this region; those with distinguished records in training and a record of community leadership. All the programs that have joined our cooperative have participated in multiple research projects over the past ten years and each program has empirical evidence of high quality treatment through prior, independent evaluations. Thus, our Cooperative has been constructed as a consortium of excellence in treatment, research and education. In this proposal we provide evidence that our Cooperative can contribute to the broader goals of changing the way addiction treatment is taught, practiced and perceived. Specifically, we will: * Direct at least one research study each year from one of three areas: 1. Controlled clinical trials of medications. 2. Controlled clinical trials of behavioral and psychosocial treatments. 3. Health Services and Practice studies of treatment access, financing and organization. * Participate in at least two additional research studies each year from the three areas. * Develop two important training and technology transfer skills. 1. Train new and existing professionals in the delivery, management and monitoring of the improved treatment methods. 2. Implement into standard practice within our Cooperative at least two medications and at least two behavioral therapies-by the end of the fifth year we will also have implemented at least one medication and one behavioral therapy into standard practice in programs outside the cooperative. * Represent the field of addiction to the world of providers, payers and policy makers, supporting medications and treatments that have been validated by the CTN.

自1974年以来，作为临床试验研究人员和治疗提供者，我们认为成瘾领域的主要需求是研究领导者和治疗提供者社区之间的合作伙伴关系。这种伙伴关系应提高这一领域的治疗和研究水平。为此，我们有费城大都会统计区作为NIDA临床试验网络的一部分。我们已经招募并培养了与该地区代表60个治疗项目的7个最好的组织的合作关系；在培训和社区领导方面有杰出记录的人。所有加入我们合作的项目在过去的十年里都参与了多个研究项目，每个项目都有经过事先独立评估的高质量治疗的经验证据。因此，我们的合作社在治疗、研究和教育方面建立了一个卓越的联盟。在本提案中，我们提供证据，证明我们的合作社可以为改变成瘾治疗的教学、实践和认知方式这一更广泛的目标做出贡献。具体来说，我们将：*每年至少从以下三个领域之一指导一项研究：药物的对照临床试验。2. 行为和心理治疗的对照临床试验。3. 卫生服务和实践研究的治疗机会，融资和组织。*每年至少参加两个以上三个领域的研究。*发展两项重要的培训和技术转移技能。1. 培训新的和现有的专业人员提供、管理和监测改进的治疗方法。2. 将至少两种药物和至少两种行为疗法纳入合作社的标准实践——到第五年年底，我们还将至少一种药物和一种行为疗法纳入合作社以外项目的标准实践。*向世界各地的提供者、付款人和政策制定者代表成瘾领域，支持经CTN验证的药物和治疗。