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中文摘要
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项目总结 华盛顿大学/俄克拉何马大学/新墨西哥大学的行政核心 卓越研究专项计划(孢子)66号路线子宫内膜癌孢子将提供 对三个项目的行政监督、宣传审查和行政支助,两个核心(生物武器、 代谢组学、病理学核心和生物统计学和生物信息学核心)和发展 研究和职业提升计划。行政核心领导将收到来自 子宫内膜癌权益组织、患者权益倡导者、内部咨询委员会和外部咨询 冲浪板。行政核心的第一个总体目标是为路线提供行政支助 66个子宫内膜癌孢子,监督所有孢子成分,包括分包和每个病例 付款分配;准备提交给国家癌症研究所的年度进展报告;与 在圣路易斯的华盛顿大学的赠款和合同办公室,并与项目主任和 国家癌症研究所的器官系统分部;并确保所有与患者的研究 参与者是道德的、尊重的、安全的,并注意到患者的需求。第二个总体目标是 通过协调每周PI为66路子宫内膜癌孢子提供组织支持 会议、指导委员会月度会议、外部咨询委员会年度会议和 年度务虚会/内部咨询委员会会议;协调参加与孢子有关的国家癌症 研究所会议;与其他子宫内膜组织协调每年一次的子宫内膜孢子研究务虚会 孢子(S);确保相关部门之间的有效沟通和研究与行政协作 这三个机构的工作人员;开发和维护66号路线的子宫内膜癌孢子 网站和月刊电子通讯。第三个目标是为企业提供科学的管理 66号路线子宫内膜癌孢子通过决定是否继续、停止或 替换完整项目以及是否将开发项目提升到完整项目的状态;协助 调查人员准备学术演示文稿、出版物、监管文件和所有其他 孢子产生的文书工作;以及加强代表性不足的少数群体对孢子的参与 无论是作为研究人员还是作为临床试验的参与者,都可以参与各种活动。第四个目标是提供 在66号公路子宫内膜癌孢子内进行的临床试验的行政服务,由 为拟议的临床试验提供支持和指导,并利用圣路易斯的华盛顿大学 机构审查委员会,用于单一地点审查。在实现这些目标时,行政核心将 帮助确保66号道路子宫内膜癌孢子实现其减轻负担的使命 子宫内膜癌。
英文摘要
PROJECT SUMMARY The Administrative Core of the Washington University/University of Oklahoma/University of New Mexico Specialized Program of Research Excellence (SPORE) Route 66 Endometrial Cancer SPORE will provide executive oversight, advocacy review, and administrative support for three projects, two cores (Biospecimens, Metabolomics, and Pathology Core and the Biostatistics and Bioinformatics Core), and the Developmental Research and Career Enhancement Programs. The Administrative Core leaders will receive advice from an Endometrial Cancer Equity Group, Patient Advocates, an Internal Advisory Board, and an External Advisory Board. The first overall objective of the Administrative Core is to provide administrative support for the Route 66 Endometrial Cancer SPORE by overseeing all SPORE components, including subcontracts and per-case payment distribution; preparing annual progress reports to the National Cancer Institute; interacting with the Grants and Contracts Office at Washington University in St. Louis and with the Program Director and Chief of the Organ Systems Branch at the National Cancer Institute; and ensuring that all research with patient participants is ethical, respectful, safe, and mindful of patients' needs. The second overall objective is to provide organizational support for the Route 66 Endometrial Cancer SPORE by coordinating weekly PI meetings, monthly Steering Committee meetings, annual meetings of the External Advisory Board, and an annual retreat/Internal Advisory Board meeting; coordinating attendance at SPORE-related National Cancer Institute meetings; coordinating an annual endometrial SPORE research retreat with other Endometrial SPORE(s); ensuring effective communication and research and administrative collaboration between relevant personnel at the three institutions; and developing and maintaining a Route 66 Endometrial Cancer SPORE website and monthly electronic newsletter. The third objective is to provide scientific management for the Route 66 Endometrial Cancer SPORE by making decisions regarding whether to continue, discontinue, or replace full projects and whether to elevate Developmental Projects to the status of full projects; assisting investigators with preparing scholarly presentations, publications, regulatory documentation, and all other paperwork generated by the SPORE; and enhancing participation of underrepresented minorities in SPORE activities, both as researchers and as participants in clinical trials. The fourth objective is to provide administrative services for the clinical trials conducted within the Route 66 Endometrial Cancer SPORE by providing support and guidance for the proposed clinical trials and using the Washington University in St. Louis Institutional Review Board for single-site review. In accomplishing these objectives, the Administrative Core will help ensure that the Route 66 Endometrial Cancer SPORE achieves its mission of reducing the burden of endometrial cancer.
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Career Enhancement Program
  • 批准号:
    10711642
  • 项目类别:
  • 资助金额:
    $10.95万
  • 财政年份:
    2023
  • 负责人:
    David G Mutch
  • 依托单位:
Project 2: Inhibiting AXL to Improve Treatment Response in Endometrial Cancer
  • 批准号:
    10711637
  • 项目类别:
  • 资助金额:
    $40.86万
  • 财政年份:
    2023
  • 负责人:
    David G Mutch
  • 依托单位:
SPORE in Endometrial Cancer
  • 批准号:
    8119020
  • 项目类别:
  • 资助金额:
    $47.5万
  • 财政年份:
    2009
  • 负责人:
    David G Mutch
  • 依托单位:
海外基金