Administrative Core

项目摘要 华盛顿大学/俄克拉荷马州大学/新墨西哥州大学的行政核心 研究卓越的专业计划（孢子）66号公路子宫内膜癌孢子将提供 执行监督、宣传审查和行政支助三个项目，两个核心（生物标本， 代谢组学、病理学核心、生物统计学和生物信息学核心），以及发展 研究和职业发展计划。行政核心领导人将从一个 子宫内膜癌权益小组，患者倡导者，内部咨询委员会和外部咨询委员会 纸板.行政核心的第一个总体目标是为路线提供行政支持 66子宫内膜癌SPORE通过监督所有SPORE组件，包括分包合同和每个病例 支付分配;准备年度进展报告，以国家癌症研究所;互动与 圣路易斯华盛顿大学赠款和合同办公室， 国家癌症研究所的器官系统分支;并确保所有与患者有关的研究 参与者是道德的，尊重的，安全的，并注意病人的需要。第二个总体目标是 通过协调每周PI，为66号公路子宫内膜癌孢子提供组织支持 会议、每月指导委员会会议、外部咨询委员会年度会议以及 年度务虚会/内部咨询委员会会议;协调出席与SPORE相关的国家癌症 研究所会议;与其他子宫内膜研究机构协调年度子宫内膜孢子研究务虚会 SPORE（s）;确保相关部门之间的有效沟通、研究和行政协作 三个机构的人员;以及开发和维护66号公路子宫内膜癌孢子 网站和每月电子通讯。三是科学管理， Route 66子宫内膜癌孢子通过决定是否继续，停止，或 替换完整项目，以及是否将发展项目提升为完整项目;协助 研究人员准备学术演讲，出版物，监管文件和所有其他 SPORE产生的文书工作;以及加强代表性不足的少数民族在SPORE中的参与 活动，无论是作为研究人员和临床试验参与者。第四个目标是提供 在Route 66子宫内膜癌SPORE内进行的临床试验的行政服务， 为拟议的临床试验提供支持和指导，并利用圣路易斯的华盛顿大学 机构审查委员会进行单中心审查。为实现这些目标，行政核心将 帮助确保66号公路子宫内膜癌孢子实现其使命， 子宫内膜癌

PROJECT SUMMARY The Administrative Core of the Washington University/University of Oklahoma/University of New Mexico Specialized Program of Research Excellence (SPORE) Route 66 Endometrial Cancer SPORE will provide executive oversight, advocacy review, and administrative support for three projects, two cores (Biospecimens, Metabolomics, and Pathology Core and the Biostatistics and Bioinformatics Core), and the Developmental Research and Career Enhancement Programs. The Administrative Core leaders will receive advice from an Endometrial Cancer Equity Group, Patient Advocates, an Internal Advisory Board, and an External Advisory Board. The first overall objective of the Administrative Core is to provide administrative support for the Route 66 Endometrial Cancer SPORE by overseeing all SPORE components, including subcontracts and per-case payment distribution; preparing annual progress reports to the National Cancer Institute; interacting with the Grants and Contracts Office at Washington University in St. Louis and with the Program Director and Chief of the Organ Systems Branch at the National Cancer Institute; and ensuring that all research with patient participants is ethical, respectful, safe, and mindful of patients' needs. The second overall objective is to provide organizational support for the Route 66 Endometrial Cancer SPORE by coordinating weekly PI meetings, monthly Steering Committee meetings, annual meetings of the External Advisory Board, and an annual retreat/Internal Advisory Board meeting; coordinating attendance at SPORE-related National Cancer Institute meetings; coordinating an annual endometrial SPORE research retreat with other Endometrial SPORE(s); ensuring effective communication and research and administrative collaboration between relevant personnel at the three institutions; and developing and maintaining a Route 66 Endometrial Cancer SPORE website and monthly electronic newsletter. The third objective is to provide scientific management for the Route 66 Endometrial Cancer SPORE by making decisions regarding whether to continue, discontinue, or replace full projects and whether to elevate Developmental Projects to the status of full projects; assisting investigators with preparing scholarly presentations, publications, regulatory documentation, and all other paperwork generated by the SPORE; and enhancing participation of underrepresented minorities in SPORE activities, both as researchers and as participants in clinical trials. The fourth objective is to provide administrative services for the clinical trials conducted within the Route 66 Endometrial Cancer SPORE by providing support and guidance for the proposed clinical trials and using the Washington University in St. Louis Institutional Review Board for single-site review. In accomplishing these objectives, the Administrative Core will help ensure that the Route 66 Endometrial Cancer SPORE achieves its mission of reducing the burden of endometrial cancer.