Mixed methods examination of warning signs within 24 hours of suicide attempt in hospitalized adults
住院成人自杀未遂 24 小时内警告信号的混合方法检查
基本信息
- 批准号:10710712
- 负责人:
- 金额:$ 80.18万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-07-01 至 2027-05-31
- 项目状态:未结题
- 来源:
- 关键词:Academic Medical CentersAccident and Emergency departmentAddressAdmission activityAdultAlgorithmsCaringCause of DeathClinicalCodeCollaborationsCrossover DesignDataDevelopmentDistalEducationEmergency treatmentEventFamilyFormulationHealthcareHospitalizationHospitalsHourIncidenceIndividualInterviewLanguageLearningLifeLinguisticsMethodologyMethodsMidwestern United StatesModelingNational Institute of Mental HealthNatural Language ProcessingPatientsPreventionProcessProviderRecording of previous eventsResearchRiskRisk AssessmentRisk EstimateRisk FactorsSamplingSignal TransductionSiteStructureSuicideSuicide attemptSuicide preventionTestingTimeTrainingTranscriptValidationWorkacute carecandidate validationclinical decision-makingclinical riskcommunity settingdeep learning modeldesigndetection methodexperiencehigh riskimprovedinnovationmembermortality risknovelpatient safetyprogramsprospectiverecruitsuicidalsuicidal actsuicidal behaviorsuicidal risksuicide ratesupport toolssystematic reviewtoolvalidation studies
项目摘要
Suicide is a leading cause of death, and individuals who attempt suicide and receive hospital treatment are at
high risk for suicide within a year. The identification and validation of warning signs (WS) for suicidal behavior –
near-term risk factors– is a national priority. Determining if an individual is at risk now drives high-impact
decisions in acute care settings within emergency departments (e.g., whether to admit a patient) and crisis
lines (e.g., whether to send a mobile crisis team). Yet, there has been little research on ‘when’ individuals are
at near-term risk or WS (i.e., within minutes, hours, a day) for suicide attempts. This clinically- and
theoretically-driven study addresses critical gaps in our understanding of WS for suicide attempts. We seek to
a) discover novel warning signs candidates for suicide attempts, b) validate, and generate the first risk
estimates, for these candidates and WS put forward in recent theoretical formulations, c) compare risk-
estimates of WS to determine if those currently prioritized in risk assessments in acute care settings is
warranted, and d) develop new algorithms to detect linguistic signals of specific WS content in patients'
narrative interviews. We propose a multi-site mixed-methods study that will recruit 400 adults currently
hospitalized for a suicide attempt in two academic medical centers in the Upper Midwest. Subjects will be
asked to tell the narrative story of their attempt in their own words, and also undergo a detailed semi-structured
interview to obtain systematic data about hypothesized WS on the day of the attempt and the day prior. We will
discover potential novel WS candidates using subjects’ narrative stories coded by experts using qualitative
methodology (Aim 1). Next, we will validate a priori and novel candidate WS (Aim 2). Case-crossover
methodology will be used, a within-subjects design that uses subjects as their own control. The semi-structured
interview data are analyzed through comparisons of the presence/intensity of hypothesized WS on the day of
the attempt (high-risk case period) to the day prior (lower risk control period). Finally, we will develop and test
an algorithm to detect linguistic signals of specific WS content (Exploratory Aim 3). Natural language
processing and deep learning models of language will be used to detect WS within the narratives. WS for
suicide attempts are extraordinarily difficult to study due the practical challenge of examining the hours
preceding an act of suicide. The project uses innovative qualitative and quantitative methods to address this
challenge in a rigorous fashion. The study is designed to provide scientifically grounded WS to inform clinical
decision-making, patient/family education, and automated risk identification.
自杀是导致死亡的一个主要原因,企图自杀并接受医院治疗的人在
项目成果
期刊论文数量(0)
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COURTNEY L BAGGE其他文献
COURTNEY L BAGGE的其他文献
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{{ truncateString('COURTNEY L BAGGE', 18)}}的其他基金
The Acute Alcohol-Suicide Attempt Relation as a Function of Alcohol Use Disorders
急性酒精与自杀企图的关系与酒精使用障碍的关系
- 批准号:
8241332 - 财政年份:2012
- 资助金额:
$ 80.18万 - 项目类别:
The Acute Alcohol-Suicide Attempt Relation as a Function of Alcohol Use Disorders
急性酒精与自杀企图的关系与酒精使用障碍的关系
- 批准号:
8515737 - 财政年份:2012
- 资助金额:
$ 80.18万 - 项目类别:
SMALL GRANT 4: SEROTONIN, IMPULSIVITY AND SUICIDE ATTEMPTS
小额资助 4:血清素、冲动和自杀企图
- 批准号:
8360512 - 财政年份:2011
- 资助金额:
$ 80.18万 - 项目类别:














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