Xenobiotic-responsive hepatic long non-coding RNAs
Xenobiotic-responsive hepatic long non-coding RNAs
批准号:
10711162
负责人:
DAVID J WAXMAN
金额:
$3.49万
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
未结题
起止时间:
2022-12-16 至 2025-04-30
关键词:
AddressAdultAffectAgonistArchitectureAutomobile DrivingAwardBioinformaticsBiological ProcessCRISPR interferenceCell CommunicationCellsChemicalsCodeData AnalysesDevelopmentDietDietary FatsDiseaseDisease ProgressionEducational StatusEpigenetic ProcessEtiologyEvaluationExposure toGene Expression ProfileGenesGenetic TranscriptionHealthHepaticHepatocyteHigh Fat DietKnockout MiceLigandsLinkLiverLiver CirrhosisLiver FibrosisLiver diseasesMediatorMentorsMetabolic PathwayMitochondriaModelingMolecularMusNuclear ReceptorsParentsPathologicPathologyPathway interactionsPhysiologicalPositioning AttributePrimary carcinoma of the liver cellsProcessProteinsQualifyingRNARegimenResearchResearch TrainingRoleSchemeSmall Nuclear RNASpecificityTechniquesTimeTrainingUnderrepresented MinorityUntranslated RNAXenobioticscell typedisorder riskdoctoral studentenvironmental chemicalenvironmental toxicologyepigenome editingexperiencefatty liver diseasegene networkimmune cell infiltratein vivoinsightinterestlaboratory experimentlipid metabolismliver metabolismmouse modelnon-alcoholic fatty liver diseasenonalcoholic steatohepatitisnovel markerparent grantprogramspromoterprototypereceptortherapeutic targettranscription factortranscription terminationtranscriptome sequencingtranscriptomic profilingunderrepresented minority student
中文摘要
多样性补充应用- ES024421, Waxman DJ, PI
英文摘要
Diversity Supplement Application – ES024421, Waxman DJ, PI
Project Summary/Abstract - This application is for a Research Supplement to Promote
Diversity in Health-Related Research (PA-21-071) in support of a qualified underrepresented
minority PhD student who will receive graduate level training in molecular environmental
toxicology under parent grant, ES024421. The proposed training and mentoring program will
use the mouse model to advance our understanding of the interactions of nuclear receptors
when activated by foreign, environmental chemicals, with exposure to high fat dietary
regimens, with a focus on interactions that impact the development and progression of fatty
liver disease. These studies are closely related to, and will significantly advance progress
under the parent grant, and will provide the qualified underrepresented minority PhD student
with training and experience in a broad range of wet lab experimental, data analysis and
bioinformatics techniques to address cutting edge research problems in molecular
environmental toxicology.
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会议论文
Growth Hormone Regulation of Sex Differences in Liver Metabolism
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批准号:9897015
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项目类别:
-
资助金额:$49.11万
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财政年份:2019
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负责人:DAVID J WAXMAN
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依托单位:
Growth Hormone Regulation of Sex Differences in Liver Metabolism
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批准号:10626011
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项目类别:
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资助金额:$49.63万
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财政年份:2019
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负责人:DAVID J WAXMAN
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依托单位:
Growth Hormone Regulation of Sex Differences in Liver Metabolism
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批准号:10402862
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项目类别:
-
资助金额:$49.5万
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财政年份:2019
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负责人:DAVID J WAXMAN
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依托单位:
Growth Hormone Regulation of Sex Differences in Liver Metabolism
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批准号:10164773
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项目类别:
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资助金额:$49.37万
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财政年份:2019
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负责人:DAVID J WAXMAN
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依托单位:
Growth Hormone Regulation of Sex Differences in Liver Metabolism
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批准号:10018890
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项目类别:
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资助金额:$50.31万
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财政年份:2019
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负责人:DAVID J WAXMAN
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依托单位:
Xenobiotic-responsive hepatic long non-coding RNAs
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批准号:10809269
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项目类别:
-
资助金额:$7.78万
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财政年份:2014
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负责人:DAVID J WAXMAN
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依托单位:
Epigenetic Actions of Environmental Chemicals
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批准号:8762618
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项目类别:
-
资助金额:$40.39万
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财政年份:2014
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负责人:DAVID J WAXMAN
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依托单位:
Xenobiotic-responsive hepatic long non-coding RNAs
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批准号:10615645
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项目类别:
-
资助金额:$47.2万
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财政年份:2014
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负责人:DAVID J WAXMAN
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依托单位:
Xenobiotic-responsive hepatic long non-coding RNAs
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批准号:10394387
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项目类别:
-
资助金额:$47.2万
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财政年份:2014
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负责人:DAVID J WAXMAN
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依托单位:
Xenobiotic-responsive hepatic long non-coding RNAs
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批准号:10210396
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项目类别:
-
资助金额:$47.2万
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财政年份:2014
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负责人:DAVID J WAXMAN
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依托单位:
Xenobiotic-responsive hepatic long non-coding RNAs
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批准号:10058507
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项目类别:
-
资助金额:$47.2万
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财政年份:2014
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负责人:DAVID J WAXMAN
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依托单位:
Cytochrome P450-Endogenous Substrate Metabolism
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批准号:8037913
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项目类别:
-
资助金额:$10.0万
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财政年份:2010
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负责人:DAVID J WAXMAN
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依托单位:
Epigenetic Marks of Xenoestrogen Exposure
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批准号:7941819
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项目类别:
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资助金额:$41.06万
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财政年份:2009
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负责人:DAVID J WAXMAN
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依托单位:
Cytochrome P450-Endogenous Substrate Metabolism
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批准号:7992597
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项目类别:
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资助金额:$9.59万
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财政年份:2009
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负责人:DAVID J WAXMAN
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依托单位:
Epigenetic Marks of Xenoestrogen Exposure
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批准号:8077724
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项目类别:
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资助金额:$8.1万
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财政年份:2009
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负责人:DAVID J WAXMAN
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依托单位:
Epigenetic Marks of Xenoestrogen Exposure
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批准号:7830420
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项目类别:
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资助金额:$40.1万
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财政年份:2009
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负责人:DAVID J WAXMAN
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依托单位:
Research Project 3: Nuclear Receptors and Gonadal Toxicity of Xenochemicals
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批准号:6901352
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项目类别:
-
资助金额:$21.42万
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财政年份:2005
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负责人:DAVID J WAXMAN
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依托单位:
PPAR, hormones, and xenobiotics
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批准号:6664578
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项目类别:
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资助金额:$13.44万
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财政年份:2002
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负责人:DAVID J WAXMAN
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依托单位:
PPAR, hormones, and xenobiotics
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批准号:6578802
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项目类别:
-
资助金额:$13.44万
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财政年份:2002
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负责人:DAVID J WAXMAN
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依托单位:
PPAR, hormones, and xenobiotics
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批准号:6443953
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项目类别:
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资助金额:$13.44万
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财政年份:2001
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负责人:DAVID J WAXMAN
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依托单位:
海外基金