Xenobiotic-responsive hepatic long non-coding RNAs

多样性补充申请-ES024421，Waxman DJ，PI 项目摘要/摘要-此应用程序是一份研究补充材料，用于推广 卫生相关研究的多样性(PA-21-071)，以支持合格的任职人数不足 将接受分子环境研究生级别培训的少数民族博士生 父母资助下的毒理学，ES024421。拟议的培训和指导方案将 利用小鼠模型促进我们对核受体相互作用的理解 当被外来的环境化学物质激活时，暴露在高脂肪饮食中 养生法，重点是影响脂肪的发展和进展的相互作用 肝病。这些研究与取得的进展密切相关，并将大大推动进展。 在家长资助下，并将提供合格的代表不足的少数族裔博士生 在广泛的湿法实验室实验、数据分析和 生物信息学技术解决分子科学前沿研究问题 环境毒理学。

Diversity Supplement Application – ES024421, Waxman DJ, PI Project Summary/Abstract - This application is for a Research Supplement to Promote Diversity in Health-Related Research (PA-21-071) in support of a qualified underrepresented minority PhD student who will receive graduate level training in molecular environmental toxicology under parent grant, ES024421. The proposed training and mentoring program will use the mouse model to advance our understanding of the interactions of nuclear receptors when activated by foreign, environmental chemicals, with exposure to high fat dietary regimens, with a focus on interactions that impact the development and progression of fatty liver disease. These studies are closely related to, and will significantly advance progress under the parent grant, and will provide the qualified underrepresented minority PhD student with training and experience in a broad range of wet lab experimental, data analysis and bioinformatics techniques to address cutting edge research problems in molecular environmental toxicology.