Imperial County Clinical Research Network for Health Equity

帝国县健康公平临床研究网络

• 批准号: 10709891
• 负责人: GUADALUPE X AYALA
• 金额: $ 125.85万
• 依托单位: SAN DIEGO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-24 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10709891
• 关键词: Address; Advisory Committees; Award; Awareness; Birth Weight; Border Community; California; Clinical Research; Cohort Studies; Collaborations; Common Data Element; Communities; Complex; Computerized Medical Record; County; Data; Data Analyses; Data Collection; Development; Disease; Education; Effectiveness; Ensure; Equity; Evaluation; Exclusive Breastfeeding; Family; Fostering; Funding; Goals; Health; Health Disparities Research; Health Personnel; Health Promotion; Healthcare; Healthcare Systems; Household; Human Resources; Income; Infant; Infrastructure; Institutional Review Boards; Interdisciplinary Study; Intervention; Knowledge; Lactation; Language; Learning; Logic; Maps; Medical center; Mental Health; Methods; Mexico; Modeling; National Institute on Minority Health and Health Disparities; Obesity; Outcome; Participant; Patients; Personal Satisfaction; Phase; Pilot Projects; Poaceae; Policies; Population; Prenatal care; Procedures; Process; Protocols documentation; Research; Research Infrastructure; Research Personnel; Research Priority; Research Support; Resources; Risk; Rural; Rural Community; Scientific Inquiry; Site; System; Testing; Time; U-Series Cooperative Agreements; Underserved Population; Weight; career; clinical practice; clinical research site; contextual factors; data harmonization; data sharing; data submission; effectiveness trial; follow-up; health disparity; health equity; implementation efforts; infrastructure development; innovation; member; minority health; minority health disparity; novel strategies; overweight child; pragmatic trial; programs; protocol development; response; secondary analysis; shared decision making; social determinants; student participation; suburb; timeline

PROJECT SUMMARY This 5-year effort titled “Leveraging a Regional Clinical Practice Research Network for Health Equity in the Rural, Border Region of Imperial County, California (Imperial County Clinical Research Network)” seeks to advance minority health and health disparities research by establishing the personnel and systems (policies and procedures) infrastructure to support clinical research within a regional medical center that serves a rural, border community in Southern California. It accomplishes this by bringing together three primary organizations and their respective leaders to develop a disease-agnostic research agenda consistent with the needs of patients, diverse clinicians and multi-sectoral community stakeholders. Infrastructure will be developed to support both observational (e.g., cohort studies; secondary analyses using electronic medical record [EMR] data) and intervention (from efficacy to effectiveness trials) research. During the UG3 phase, we propose to develop the research infrastructure to support the implementation of a pragmatic trial as this provides the strongest possible infrastructure for supporting PP2, which will be determined through a competitive process. The UG3 phase also will advance data sharing activities including identifying a set of common data elements across Network sites, and developing and testing protocols and systems for sharing data, including EMR data from multiple systems. During the UH3 phase (Y3-5), both PPs will be launched following final approval from the Multidisciplinary Research Council and the SDSU IRB committee. PP1 proposes to test a robust Lactation Support Program to promote engagement in prenatal care and exclusive breastfeeding to ultimately reduce the rates of childhood overweight and obesity in Imperial County. The UH3 phase will continue to advance data sharing and promote dissemination through the development of protocols and systems for data verification, data harmonization, and meaningful interpretation of data given contextual factors (e.g., language of administration). The proposed timeline plans for data sharing and harmonization to occur with the PPs as early as possible (here in Y3), and with sufficient time at the end to complete final follow-up data collection from participants, and data submitted to the Coordinating Center in Y5. All of these efforts will be guided by the involvement of a Patient Advisory Committee (5 members), a Clinician Advisory Committee (15 diverse clinician types), and a Community Stakeholder Committee (12 diverse sector members). The ultimate goal of this effort is to identify feasible, sustainable, and translatable approaches to promote health and well-being in rural, border communities.

项目总结 这项为期5年的工作名为“利用区域临床实践研究网络促进农村卫生公平， 加利福尼亚州帝国郡边境地区(帝国郡临床研究网络)“寻求推进 通过建立人员和制度(政策和制度)来研究少数民族健康和健康差距 程序)基础设施，以支持为农村边境地区服务的区域医疗中心内的临床研究 南加州的社区。它通过将三个主要组织及其 各自领导制定符合患者需求的疾病不可知研究议程，多样化 临床医生和多部门社区利益相关者。将发展基础设施，以支持这两个 观察性(例如，队列研究；使用电子病历[EMR]数据的二次分析)和 干预(从疗效到有效性试验)研究。在UG3阶段，我们建议开发 支持实施务实试验的研究基础设施，因为这提供了最强有力的 支持PP2的基础设施，这将通过竞争过程确定。UG3阶段还 将推进数据共享活动，包括识别跨网络站点的一组公共数据元素， 以及开发和测试用于共享数据的协议和系统，包括来自多个系统的电子病历数据。 在UH3阶段(Y3-5)，这两个PPS将在获得多学科的最终批准后推出 研究理事会和SDSU IRB委员会。PP1建议测试强大的哺乳支持计划，以 促进产前护理和纯母乳喂养，最终降低儿童期发病率 帝国郡的超重和肥胖。UH3阶段将继续推进数据共享和促进 通过制定数据核查、数据统一和协调的协议和系统进行传播 考虑到背景因素(例如，行政语言)，对数据进行有意义的解释。建议数 尽早与PPS共享和统一数据的时间表计划(在第三年)；以及 在结束时有足够的时间完成从参与者那里收集的最终后续数据，并将数据提交给 Y5中的协调中心。所有这些工作都将由一名患者顾问参与指导 委员会(5名成员)、临床医生咨询委员会(15种不同的临床医生类型)和社区 利益攸关方委员会(12名不同部门成员)。这一努力的最终目标是确定可行的、 促进农村和边境社区健康和福祉的可持续和可翻译的方法。