NICHD SERVICES: MPT DATABASE ACCESS AND MAINTENANCE

倡议的科学合理性： 与美国国际开发署达成机构间协议，支持CAMI Health扩大非荷尔蒙MPTS领域(Y01)--请注意：CAMI是 名称，而不是缩写或首字母缩写。 NICHD尚未举行2020财年艾滋病毒/艾滋病规划会议，因此以后可能需要修改这一理由。 多用途技术有可能保护妇女和女孩免受相互关联的性健康和生殖健康风险。《倡议》 多用途预防技术(IMPT)是CAMI-Health的项目，CAMI-Health是一个致力于改善妇女健康的组织 和世界各地的女孩，居住在公共卫生研究所(PHI)。 过去，CRB资助Cami-Health让IMPT协调MPT领域，主要是以激素为基础的产品的方向， 因此，该领域一直集中在这一领域。在过去的两年里，避孕研究部和妇产科 儿科传染病科开始合作，目标是开发既有避孕药又有避孕药的非荷尔蒙MPT 以及预防艾滋病毒的特性。这代表着过去十年的研究范式发生了转变，过去十年的研究主要集中在 以激素为基础的MPTS的开发。这一倡议旨在利用IMPT的重要经验、技能和资源来推动 开发非激素的MPTS，并协助吸引来自该领域的研究人员，建立活跃的和 感兴趣的研究人员，促进全球研究参与/伙伴关系，并改善非激素领域的行业参与 MPTS。 倡议背景： 多用途技术(MPTS)代表了一种非常有希望的将避孕与艾滋病毒预防相结合的方法，并提供了 有吸引力的公共卫生方法。近年来，Cami-Health在协调多种用途方面发挥了强大的作用 技术领域，主要重点是推动基于激素的MPTS的发展。这项继续资助本协会的请求 允许CRB和MPIDB利用与Cami-Health的关系来增加IMPT在以下方向的活动 开发不基于荷尔蒙作用的新颖、创新的MPT。 去年，档案局已开始这方面的资助工作，MPIDB将在不久的将来颁发奖项。这一地区意义重大 两个分支机构都感兴趣。 这一倡议的目标是什么？ 这一倡议的目标是让IMPT利用其在该领域的专业知识来提高认识，并刺激更多的全球 对非荷尔蒙MPT发育的活性。这包括但不限于提高全球研究人员的认识 资助机构和行业。 2020财年艾滋病信息中心申请 NICHD (千美元) 计划理由第18页，共19页打印时间：下午4：43 打印日期：2018年7月5日 ·每年组织和主办1-2次技术网络研讨会，模拟与以下主题相关的障碍和机会的讨论 非激素性MPTS的发展。示例包括： 1.非激素性MPTS的发展； 二、跨技术平台合作，以综合方式应对挑战。·向利益攸关方开发、修订和传播与MPT相关的非荷尔蒙外展材料。 这项工作可能会得到改进，并可能通过与避孕研究处、妇产科和妇产科的讨论来增加新的活动 儿科传染病处和多用途预防技术倡议。 将每季度审查进展情况，并根据为实现协议目标而开展的有意义的活动来衡量进展情况。在……里面 在接下来的几个月里，特拉维斯·肯特博士将作为AAAS研究员加入CRB，预计他将成为关键 这些活动的参与者。

Scientific Justification of Initiative: Interagency Agreement with USAID to Support CAMI Health to Expand the Field of Nonhormonal MPTs (Y01) - please note: CAMI is a name, not an abbreviation or acronym. NICHD has not yet had its FY2020 HIV/AIDS planning session so changes to this justification may be needed later. Multi-Purpose Technologies have the potential to protect women and girls from interlinked sexual and reproductive health risks. The Initiative for Multipurpose Prevention Technologies (IMPT) is a project of CAMI-health, an organization dedicated to improving the health of women and girls worldwide, housed at the Public Health Institute (PHI). In the past the CRB funded CAMI-health to have the IMPT coordinate the MPT field, primarily in the direction of hormonally based products, and as a result the field has been focused in that area. In the past two years, the Contraception Research Branch and the Maternal and Pediatric Infectious Disease Branch have begun collaborating with the goal of developing nonhormonal MPTs that have both contraceptive and HIV-prevention properties. This represents a paradigm shift away from research of the past decade which has focused primarily on the development of hormonally based MPTs. This initiative seeks to employ IMPT's significant experience, skill and resources to advance the development of nonhormonal MPTs and assist in attracting researchers from the field, establish meetings and teleconferences of active and interested researchers, facilitate global research engagement/partnership and improve industry engagement in the area of nonhormonal MPTs. Initiative Background: Multipurpose Technologies (MPTs) represent a very promising approach for combining contraception with HIV prevention and provide an attractive public health approach. In recent years the IMPT of CAMI-health has been a strong presence in coordinating the multipurpose technology field, with the primary focus of driving the development of hormone based MPTs. This request to continue funding of this IAA allows the CRB and the MPIDB to leverage the relationship with CAMI-health to increase the activity of the IMPT in the direction of developing novel, innovative MPTs that are not based on hormonal action. In last year, the CRB has begun funding work in this area and the MPIDB will make awards in the near future. The area is of significant interest to both branches. What are the goals of this initiative? The goals of this initiative are for IMPT to use its expertise and knowledge of the field to increase awareness and stimulate more global activity on nonhormonal MPT development. This includes but is not limited to increasing awareness on the part of researchers, global funding agencies and industry. FY 2020 AIDS IC Request NICHD (Dollars in Thousands) Initiative Justification Page 18 of 19 Print Time: 4:43 PM Print Date: 7/5/2018 · Organize and host 1-2 technical webinars annually on topics to simulate discussion of barriers and opportunities related to the development of nonhormonal MPTs. Examples include: i. development of nonhormonal MPTs; ii. working across technology platforms to approach challenges in an integrated manner. · Develop, revise, and disseminate nonhormonal MPT-related outreach materials to stakeholders. The work may be refined, and new activities may be added through discussions with the Contraception Research Branch, the Maternal and Pediatric Infectious Disease Branch and the Initiative for Multipurpose Prevention Technologies. Progress will be reviewed quarterly and measured based on the conduct of meaningful activities to fulfill the objectives of the agreement. In the coming months, Dr. Travis Kent will become associated with the CRB as an AAAS Fellow, and it is expected that he will become a key participant in these activities.