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Proteomic biomarkers for radiation injury and countermeasure efficacy

Proteomic biomarkers for radiation injury and countermeasure efficacy
放射损伤的蛋白质组生物标志物及对策效果
批准号：
10723267
负责人：
Vijay Singh
金额：
$10.0万
依托单位：
OFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEALTH
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/10723267
关键词：
AnimalsBiologicalBiological MarkersDataDevelopmentDoseExperimental ModelsExposure toGamma RaysIndividualInterleukin-11Molecular TargetPrediction of Response to TherapyProteomicsRadiation InjuriesResearch Project GrantsSamplingSubcutaneous InjectionsTreatment outcomeanalogirradiationnonhuman primatepre-clinicalradiation countermeasureradiation mitigator

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英文摘要
The overall objective of this research project is to determine proteomic biomarkers of irradiation in preclinical experimental models of non-human primates (NHP). These data may permit prediction of treatment outcomes for individuals exposed to γ-radiation over the long term. Additionally, such biomarkers may help identify molecular targets useful for the development of promising radiomitigators.
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