Mitochondrial Retrograde Signalling in Plants – New Models and Analytical Approaches

植物中的线粒体逆行信号传导 – 新模型和分析方法

• 批准号: DP140100321
• 负责人: Prof James Whelan
• 金额: --
• 依托单位: La Trobe University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2014-02-28
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP140100321
• 关键词: Mitochondrial; Retrograde; Signalling; Plants; New

Mitochondria are essential organelles involved in energy production and various metabolic and biosynthetic pathways in plant cells. Signals from mitochondria act to regulate nuclear gene expression to coordinate mitochondrial activity with cellular activity, which is called mitochondrial retrograde signalling (MRS). To date our knowledge of the pathways and components involved in MRS is limited to a single model system. This proposal seeks to identify additional MRS pathways, characterise components of these pathways and the signals involved. This new knowledge can be used in translational research as a basis to breed plants with altered stress and growth properties.

线粒体是植物细胞中参与能量产生和各种代谢和生物合成途径的重要细胞器。来自线粒体的信号调节核基因表达，协调线粒体活动和细胞活动，这被称为线粒体逆行信号（MRS）。迄今为止，我们对MRS中涉及的通路和成分的了解仅限于单一的模型系统。本提案旨在确定额外的MRS通路，表征这些通路的组成部分和所涉及的信号。这一新知识可用于转化研究，作为培育具有改变胁迫和生长特性的植物的基础。