The role of serotonin in emotional processing

血清素在情绪处理中的作用

• 批准号: 7137923
• 负责人: james r blair
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF MENTAL HEALTH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7137923
• 关键词: amygdala; behavioral /social science research tag; cognition; emotions; frontal lobe /cortex; human subject; negative reinforcements; neural information processing; neuroimaging; neuropsychological tests; neuropsychology; serotonin

The goal of this protocol is to use a targeted serotonergic manipulation (tryptophan depletion) and specific neurocognitive and neuroimaging paradigms to consider the role of serotonin in emotional processing. In particular, we will evaluate claims that serotonin has a role in the effective processing of aversive signals. In addition, we will examine whether tryptophan depletion will attenuate the neural response to aversive material.

该方案的目标是使用有针对性的5-羟色胺能操纵(色氨酸耗竭)和特定的神经认知和神经成像范例来考虑5-羟色胺在情绪处理中的作用。特别是，我们将评估5-羟色胺在有效处理厌恶信号方面的作用。此外，我们还将研究色氨酸缺乏是否会减弱神经对厌恶物质的反应。