Mayo Clinic Vascular Medicine Clinical Research Training Program

描述（由申请人提供）： 动脉、静脉和动脉系统的疾病是常见的，并且经常是致命的，引起慢性疼痛和损伤，并且由于医疗保健费用和收入损失而产生大量费用。很少有医生接受过足够的培训来照顾血管疾病患者，更少的医生在血管疾病方面进行转化研究，这主要是因为血管医学的多学科临床研究培训几乎不存在。该提案的长期目标是建立一个马约诊所血管医学-临床研究培训计划（VM-CRTP），并提供临床血管医学和以患者为导向的研究方面的综合培训。为了实现这一目标，我们提出了一个多学科的课程，在临床血管医学，血管生物学和转化研究，包括研究导师与既定的调查。拟议的计划将利用马约诊所现有的几个资源：（1）国际公认的多学科血管中心，为大量动脉，静脉和淋巴疾病患者提供护理;（2）两个NIH资助的（K30和K12）临床研究培训计划;（3）30多名从事血管医学相关研究的研究者/导师;以及（4）通过K25机制培训和招募美洲原住民、妇女和经济发展中大学学员的若干举措。马约诊所VM-CRTP的具体目标是：1）在动脉、静脉或淋巴疾病患者的诊断和护理方面制定多学科临床培训计划; 2）开发关于流行病学原理的综合教学工具（包括遗传流行病学）和生物统计学，卫生保健经济学，血管生物学，以及预防，诊断和治疗动脉，静脉和淋巴疾病;和3）制定一个教学和指导计划的设计，进行和临床转化研究的分析。该拨款申请旨在为课程开发和整合，候选人识别和招聘，临床培训和研究指导提供资金。公共卫生声明：这项研究将教会医生如何照顾血管疾病的患者，包括动脉，静脉和淋巴管疾病。此外，这项研究还将教会医生如何发现动脉、静脉和淋巴管疾病的新原因，以及预防和治疗这些疾病的新方法。

DESCRIPTION (provided by applicant): Diseases of the arteries, veins, and lymphatics are common and frequently lethal, cause chronic pain and impairment, and incur substantial costs due to health care charges and lost earnings. Few physicians are adequately trained to care for patients with vascular diseases and even fewer perform translational research in vascular diseases, largely because multidisciplinary clinical research training in vascular medicine is virtually non-existant. The long-term goal of this proposal is to establish a Mayo Clinic Vascular Medicine-Clinical Research Training Program (VM-CRTP) and provide comprehensive training in both clinical vascular medicine as well as patient-oriented research. To accomplish this goal, we propose a multidisciplinary curriculum in clinical vascular medicine, vascular biology and translational research, including a research mentorship with an established investigator. The proposed program will leverage several resources already available at the Mayo Clinic: (1) an internationally recognized multidisciplinary Vascular Center that provides care for a large number of patients with arterial, venous, and lymphatic diseases; (2) two NIH-funded (K30 and K12) clinical research training programs; (3) over 30 investigator/mentors engaged in research relevant to vascular medicine; and (4) several initiatives to train and recruit Native Americans, women, and trainees from economically developing universities through a K25 mechanism. The specific aims of the Mayo Clinic VM-CRTP are: 1) to develop a multidisciplinary clinical training program in the diagnosis and care of the patient with arterial, venous or lymphatic diseases; 2) to develop comprehensive teaching tools on the principles of epidemiology (including genetic epidemiology) and biostatistics, health care economics, vascular biology, and the prevention, diagnosis and treatment of arterial, venous and lymphatic diseases; and 3) to develop a teaching and mentoring program in the design, conduct and analysis of clinical translational research. This grant application seeks funding for curriculum development and integration, candidate identification and recruitment, clinical training, and research mentorship. Public Health statements: This research will teach doctors how to take care of patients with diseases of the blood vessels, including diseases of arteries, veins and lymph vessels. In addition, this research will teach doctors how to discover new causes of diseases of arteries, veins and lymph vessels, as well as new ways to prevent and treat these diseases.