Telephone Counseling: Men w/Prostate CA & Partners

描述(申请人提供)：这项初步研究的目的是测试电话传递的人际咨询干预措施与关注的日常护理对照对80名前列腺癌患者及其伴侣的生活质量(身体、心理、社会和精神健康)的影响。目的1比较电话人际咨询干预(TIP-C)和注意力日常护理对照(UC)对前列腺癌患者及其伴侣a)身体健康(疲劳、症状困扰和症状管理)b)心理健康(抑郁、焦虑和压力)、c)社会健康(关系质量)和d)精神健康的有效性。目标2将描述那些对TIP-C干预措施做出积极反应的个人(癌症患者和伴侣)的人口统计数据(例如，年龄、种族)和社会概况。减少抑郁、消极情绪、压力、焦虑、疲劳和症状困扰的症状，增加社会幸福感、症状管理、关系质量和精神幸福感)。第三个目标侧重于可行性问题(即解决电话提供的干预措施的任何后勤问题)。目的4审查相关的方法学问题(即，确定每次干预的效果大小差异、与治疗强度相关的剂量-反应、预期结果所需的坚持程度)。这项研究将使用具有重复测量的随机分层实验设计来比较8周的TIP-C干预和8周的UC对生活质量指标的有效性。大约80名患有前列腺癌的白人、非西班牙裔和西班牙裔男性及其伴侣(N=160)将被分配到TIP-C或UC，按阶段(IA至IV)分层。测量将进行五次：在登记时的基线(T1)，完成三周的干预(T2)，完成六周的干预(T3)，完成8周的干预(T4)和T4之后的两个月(T5)，无论分组分配如何。数据将通过描述性统计、一系列双向混合设计ANOVA和个体回归分析进行分析。

DESCRIPTION (provided by applicant): The purpose of this pilot study is to test a telephone-delivered interpersonal counseling intervention compared to an attentional usual care control on the effects of quality of life (physical, psychological, social and spiritual well-being) for 80 men with prostate cancer and their partners. Aim 1 will examine the effectiveness of the telephone interpersonal counseling intervention (TIP-C) compared to an attentional usual care control (UC) with men with prostate cancer and their partners' a) Physical well-being (fatigue, symptom distress and symptom management) b) Psychological well-being (depression, anxiety, and stress), c) Social Well-being (relationship quality) and d) Spiritual Well-Being. Aim 2 will describe the demographic (e.g., age, ethnicity) and social profiles of those individuals (person with cancer and partner) who respond positively to the TIP-C intervention, (e.g.. decreased symptoms of depression, negative affect, stress, anxiety, fatigue, and symptom distress and increased social well-being, symptom management, relationship quality and spiritual well-being). The third aim focuses on feasibility issues (i.e., to resolve any logistical issues of the telephone-delivered interventions). Aim 4 examines relevant methodological issues (i.e., determining the effect size differences for each intervention, dose- response associated with treatment strength, level of adherence needed for the desired outcomes). This study will use a randomized, stratified experimental design with repeated measures to compare the effectiveness of an 8 week TIP-C intervention with an 8-week UC on QOL indicators. About 80 white, non- Hispanic and Hispanic men with prostate cancer and their partners (N=160) will be assigned to either the TIP-C or UC, stratified by stage (IA to IV). Measurement will occur five times: At baseline upon enrollment (T1), after completing three weeks of the interventions (T2), after completing 6 weeks of the interventions (T3), after completing the 8-week interventions (T4) and two months after T4 (T5) for all subjects, regardless of group assignment. Data will be analyzed through descriptive statistics, a series of two-way mixed design ANOVAs and individual regression analyses.