Endocrine, Diabetes and Metabolism Training Program

描述（由申请人提供）：约翰霍普金斯大学细胞和分子内分泌学跨部门培训计划的目标是培养与内分泌和内分泌疾病相关的生物医学科学医生和博士后。项目主任将与指导委员会合作，从两类极具天赋的个人中选择候选人：1)约翰霍普金斯大学内分泌研究员，已完成一年的临床内分泌培训；2)来自约翰霍普金斯大学和其他机构的医学博士和博士申请者，对基础实验室培训有浓厚兴趣。选择不仅基于个人的资格和兴趣，还基于他们将基础科学应用于临床问题的潜力和承诺。培训计划包括至少两年的密集基础科学实验室工作，由16名感兴趣的导师指导，这些导师的兴趣涉及分子和细胞生物学、膜蛋白生物化学、遗传学、细胞生理学和发育生物学的广泛概念。学员将学习和使用实验室技术，包括重组DNA和RNA操作，转基因技术，蛋白质生物化学，电生理学，细胞和组织培养，以及免疫学作为应用内分泌问题。除了基本的实验室工作，受训者还将参加由研究研讨会、期刊俱乐部、临床会议和正式课程组成的课程，这些课程由受训者、导师和项目主任共同决定选择。临床经验限于每月在门诊内分泌诊所进行2至4次半天的会议。美国国立卫生研究院资助的普通临床研究中心为受训者提供了一个发展临床研究方案的机会，以补充他们的实验室研究，并发现转化研究的潜在好处。该计划的主要目标是培养学术内分泌学家，他们作为独立的实验室科学家，能够提出假设并制定研究计划，解决当代内分泌问题。医学博士候选人有资格参加内分泌或儿科内分泌亚专业委员会。

DESCRIPTION (provided by applicant):The goal of the Interdepartmental Training Program in Cellular and Molecular Endocrinology at Johns Hopkins is to train physicians and postdoctoral fellows in biomedical science related to endocrinology and endocrine disease. The Program Director will work with a Steering Committee to choose candidates from two pools of highly talented individuals: 1) endocrine fellows at Johns Hopkins who have completed one year of clinical endocrine training, and 2) M.D. and Ph.D. applicants from this and other institutions who have a strong interest in fundamental laboratory training. Selection will be based not only on an individual's qualifications and interests, but also on their potential and commitment to applying fundamental science to clinical problems. The training program consists of at least two years of intensive basic science laboratory work under the direction of sixteen preceptors whose interests fall within the broad concepts of molecular and cellular biology, membrane protein biochemistry, genetics, cellular physiology, and developmental biology. Trainees will learn and use laboratory techniques including recombinant DNA and RNA manipulations, transgenic technology, protein biochemistry, electrophysiology, cell and tissue culture, and immunology as applied endocrine problems. In addition to basic laboratory work, trainees will participate in a curriculum that consists of research seminars, journal club, clinical conferences, and formal courses to be selected by mutual decision between the trainee, the preceptor, and the Program Director. The clinical experience is limited to 2 to 4 half-day sessions per month in an Outpatient Endocrine Clinic. The availability of an NIH-funded General Clinical Research Center provides trainees with an opportunity to develop clinical research protocols that complement their laboratory studies, and to discover the potential benefits of translational research. The major goal of this program is to train academic endocrinologists who function as independent laboratory scientists capable of developing hypotheses and creating research plans that address contemporary endocrine problems. M.D. candidates are eligible to sit for the Endocrine or Pediatric Endocrinology subspecialty boards.