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Evaluation of the Inflammatory Responses Evoked by SARS

Evaluation of the Inflammatory Responses Evoked by SARS
SARS 引起的炎症反应的评估
批准号：
6809408
负责人：
ADRIANA R MARQUES
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/6809408
关键词：
Coronaviridae cytokine enzyme linked immunosorbent assay human tissue immunoregulation inflammation interferons microorganism immunology pathologic process polymerase chain reaction questionnaires respiratory infections

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中文摘要
翻译
严重急性呼吸系统综合症（SARS）是一种新认识的疾病，具有很高的发病率和死亡率。病人先是发烧，接着是迅速发展甚至致命的呼吸道疾病。SARS与一种新型冠状病毒感染有关。对SARS引起的炎症反应的评估可以提供有关其发病机制的信息，并有助于患者的管理。我们的目标是研究疾病的发病机制和自然史，通过研究由外部医生或临床中心医生收集的样本和数据，并发送给炎症反应评估。
英文摘要
Severe acute respiratory syndrome (SARS) is a newly recognized illness associated with substantial morbidity and mortality. Patients develop fever followed by rapidly progressive and even fatal respiratory disease. SARS is associated with infection with a novel coronavirus. The evaluation of the inflammatory responses evoked by SARS may yield information regarding its pathogenesis and help with patient management. We aim to study disease pathogenesis and natural history, by studying samples and data that are collected by outside physicians or physicians at the Clinical center and sent for evaluation of the inflammatory response.
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