Stimulus- Evoked Vestibular Evaluation System

描述（由申请人提供）：Vesticon正在开发一种刺激诱发前庭评估系统（SEVE），用于检测/分析引起头晕或不平衡的声音和压力引起的症状，用于医疗机构。这些情况构成了导致头晕/不平衡主诉的所有疾病的很大一部分。总共有620万美国人长期受到头晕和失衡失调的影响，其中与平衡有关的跌倒占老年人意外死亡的一半以上。虽然可以进行治疗，但诊断存在重大问题，原因和症状多种多样，需要先进的技术来协助检测/分析。目前的技术仅限于功能单一、操作困难、无解释性的产品，既不全面也不省时。SEVE将自动诊断和定位在文献中众所周知的测试，但由于实用性、缺乏标准化和培训，这些测试经常被忽视，没有正确执行或根本没有执行。

DESCRIPTION (provided by applicant): Vesticon is developing a Stimulus-Evoked Vestibular Evaluation System (SEVE) for detection/analysis of sound and pressure evoked manifestations of conditions causing dizziness or imbalance for application at medical facilities. Such conditions comprise a significant portion of all disorders resulting in complaints of dizziness/imbalance. In all, dizziness and imbalance disorders chronically affect 6.2 million Americans, where balance-related falls account for more than half of accidental deaths in the elderly. Although treatment is available, diagnosis poses a significant problem with diverse causes and symptoms requiring advanced technology to assist in the detection/analysis. Current technology is limited to single-function, difficult-to-operate, non- interpretative products, which are neither comprehensive nor time-efficient. SEVE will automate diagnostic and localizing tests that are well known in the literature, but are often discounted, not performed correctly or not performed at all due to practicality, and lack of standardization and training. Recently, Ph. I work was completed where we developed a working prototype and demonstrated the value of SEVE in a small subject cohort and assessed user friendliness. For Ph. II, we anticipate developing several novel protocols, adding additional testing and functionality, engineering modifications, enhancing software for diagnostic protocols, interpretation, integrative analysis for decision support, and evaluating SEVE's performance with a subject population at the PI's clinic and 2 independent sites.