Fiber Laser For Myringotomy And Middle-Ear Surgery

用于鼓膜切开术和中耳手术的光纤激光器

• 批准号: 7493967
• 负责人: KURT J LINDEN
• 金额: $ 43.49万
• 依托单位: SPIRE CORPORATION
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-06-25 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7493967
• 关键词: Ablation; Acoustics; Address; Adenoidectomy; Animal Model; Animals; Area; Bone Tissue; Boston; Burn injury; Caliber; Carbon Dioxide; Cauterization - action; Chickens; Child; Chinchilla (genus); Condition; Deposition; Dimensions; Doctor of Medicine; Ear; Equipment; Exhibits; Eye; Facial nerve structure; Fascia; Fiber; Fluorides; Gases; Histocompatibility Testing; Housing; Ions; Lasers; Length; Life; Light; Manufacturer Name; Massachusetts; Microsurgery; Operative Surgical Procedures; Optics; Organism; Otolaryngologist; Otologic Surgical Procedures; Output; Pediatric Hospitals; Performance; Phase; Physiologic pulse; Power Sources; Procedures; Pulse taking; Pump; Qualifying; Reporting; Research Personnel; Simulate; Surface; Temporal bone structure; Testing; Thick; Tilia; Time; Tissues; Tonsillectomy; Tympanic membrane; Tympanostomy; Vacuum; Water; Work; absorption; beef; density; design; experience; falls; improved; instrument; lens; middle ear; optical fiber; programs; research and development; research clinical testing; scale up; scalpel; size; skull base; solid state

DESCRIPTION (provided by applicant): The objective of the Proposed Phase II program is to design, fabricate, and demonstrate a 4 W, 2712 nm fiber laser for use in myringotomy and middle ear surgery. This wavelength is near a maximum in the water absorption spectrum, thereby reducing the laser power requirement. Current myringotomy and middle-ear surgery generally involves the use of a scalpel. Some myringotomy and middle-ear procedures utilize CO2, or various solid-state lasers, but these lasers are large, expensive, and sparsely used. Pulsed lasers result in acoustic pops, frightening children and precluding further usage. Phase I successfully demonstrated a 1 W, continuous wave, 2712 nm fiber laser, capable of burning circular sub-mm diameter holes in a variety of chicken and beef tissue. The Phase II aims will be to scale up the current fluoride fiber laser dimensions, design and apply fiber optical end-coatings for reflectivity control and fiber material passivation, and to fabricate and demonstrate operation of this laser for myringotomy and middle ear surgery applications. Fiber laser efficacy in drilling clean holes into various types of tissue will be tested. Animal models will be used in the second year to determine laser efficacy on living organisms.

描述（由申请方提供）：拟定II期项目的目的是设计、制造和演示用于鼓膜切开术和中耳手术的4 W、2712 nm光纤激光器。该波长接近水吸收光谱中的最大值，从而降低了激光功率要求。目前的鼓膜切开术和中耳手术通常涉及手术刀的使用。一些鼓膜切开术和中耳手术使用CO2或各种固态激光器，但这些激光器体积大，价格昂贵，且很少使用。脉冲激光会产生声爆，吓到孩子，阻止进一步使用。第一阶段成功展示了1 W、连续波、2712 nm光纤激光器，能够在各种鸡肉和牛肉组织上烧出直径小于mm的圆孔。第二阶段的目标将是扩大目前的氟化物光纤激光器的尺寸，设计和应用光纤末端涂层，用于反射率控制和光纤材料钝化，并制造和演示该激光器用于鼓膜切开术和中耳手术应用的操作。将测试光纤激光器在各种类型的组织中钻干净孔的功效。第二年将使用动物模型来确定激光对生物体的疗效。