Biocomputing Core

介绍 生物计算核心将为Siteman CCNE提供集中的计算和存储资源 （SCCNE）项目，并作为项目和caBIG之间的联系点。的数据密集 许多拟议的SCCNE项目的性质要求 需要集中的存储和计算设施。几 这些项目需要具备归档、分析和 搜索/访问数千TB的常见原始 和元数据;所有项目都必须提供数据， 向更广泛的癌症社区传播。集中式资源 有几个好处首先，它消除了冗余的需求。 硬件基础设施和管理人员。二是 促进项目之间的互动，确保共同的 访问数据的机制。第三，它简化了 通过提供共同的， 用于caGRID访问的软件/硬件基础设施， 用于迁移到符合cabig标准的数据的集中化专业知识 标准和格式。 考虑到这些因素，核心有以下几点： 支持“目标”：提供集中存档的存储支持 资源的大量数据所产生的 项目;为促进执行提供计算支持 并执行数据分析和推理功能 各种项目;以及cabig合规服务，以确保 及时向其他人分发项目数据和软件 研究人员通过CAGRID。正如这些目标所表明的那样， 生物计算核心的核心是作为一个“计算交换所”的数据和算法产生的 SCCNE项目：我们将为项目提供存储和计算资源，我们将确保 数据和算法被转换为符合cabig的格式，我们将使数据在 caGRID的时间由项目调查人员决定。

Introduction The Biocomputing Core will provide centralized computing and storage resources for the Siteman CCNE (SCCNE) projects and serve as the point of contact between the projects and caBIG. The data-intensive nature of many of the proposed SCCNE projects mandates the need for a centralized storage and compute facility. Several of the projects require the ability to archive, analyze, and search/access thousands of terabytes of common sets of raw and meta-data; all of the projects must provide data they generate to the wider cancer community. A centralized resource has several benefits. First, it eliminates the need for redundant hardware infrastructure and administrative personnel. Second, it facilitates interaction between the projects by ensuring common mechanisms for access to the data. Third, it simplifies the interaction with the caBIG community by providing common software/hardware infrastructure for caGRID access and centralized expertise for migration to caBIG-compliant data standards and formats. Given these considerations, the Core has the following support "aims": storage support to provide centralized archival resources for the massive amounts of data generated by the projects; computational support to facilitate the implementation and execution of data analysis and inference functions of the various projects; and caBIG-compliance services to ensure the timely distribution of project data and software to other researchers via caGRID. As illustrated by these aims, the goal of the Biocomputing Core is to act as a "computational clearinghouse" for data and algorithms generated by the SCCNE projects: we will provide storage and computational resources for the projects, we will ensure the data and algorithms are converted to caBIG-compliant formats, and we will make the data available on the caGRID at times determined by the project investigators.