Adapting and Implementing a Chronic Disease Self-Management Program for Primary Care Patients with Opioid Use Disorder and Serious Mental Illness

针对患有阿片类药物使用障碍和严重精神疾病的初级保健患者调整和实施慢性病自我管理计划

• 批准号: 10785110
• 负责人: Elizabeth Siantz
• 金额: $ 18.66万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-30 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10785110
• 关键词: Address; Adoption; Adult; Area; Behavior; Buprenorphine; Caring; Chronic Disease; Clinic; Clinical; Clinical Investigator; Clinical Trials; Clinical Trials Design; Communities; Complex; Disease; Disease Management; Dissemination and Implementation; Doctor of Philosophy; Education; Educational Intervention; Environment; Ethnography; Evidence based treatment; Feasibility Studies; Formulation; Foundations; Future; Goals; Health; Health education; Helping to End Addiction Long-term; Hybrids; Improve Access; Intervention; Interview; Leadership; Mental Health Associations; Mental Health Services; Mentored Research Scientist Development Award; Mentors; Methods; Naltrexone; Outcome; Participant; Patient Education; Patients; Persons; Pharmaceutical Preparations; Pilot Projects; Population; Positioning Attribute; Primary Care; Procedures; Process; Provider; Qualitative Evaluations; Quality of Care; Randomized; Reporting; Research; Research Personnel; Resources; Science; Scientist; Self Management; Services; Site; Social Workers; Statistical Data Interpretation; Symptoms; Testing; Time; Training; Training Activity; United States National Institutes of Health; acceptability and feasibility; addiction; career; career development; contextual factors; design; education resources; effectiveness study; ethnographic method; evidence base; experience; feasibility testing; gaps in access; gender diversity; gender equity; health related quality of life; high risk; implementation barriers; implementation context; implementation evaluation; implementation facilitators; implementation intervention; implementation process; implementation research; implementation science; improved; innovation; medication for opioid use disorder; mortality; novel; opioid epidemic; opioid overdose; opioid use disorder; patient population; peer; physical conditioning; primary care clinic; primary care patient; primary care provider; primary care services; primary care setting; programs; randomized trial; satisfaction; self-management program; severe mental illness; skill acquisition; skills; social health determinants; social vulnerability; systematic review; tool; treatment as usual

This K01 award application is for Dr. Elizabeth Siantz, a PhD-trained social worker whose overarching career goal is to become an independent clinical investigator who uses implementation science to promote the adoption and integration of evidence-based Chronic Disease Self-Management programs for persons with chronic disease, primarily opioid use disorder (OUD) and serious mental illness (SMI). This K01 will support four key areas of career development: 1) intervention adaptation as it relates to the mental health and primary care needs of persons with OUD; 2) training in clinical trial design and management in real-world settings; 3) advanced skills for qualitatively evaluating intervention implementation; and 4) strengthening research leadership with a focus on gender equity and diversity in science. Dr. Siantz has assembled an interdisciplinary mentoring team comprised of Adam Gordon, MD (Primary Mentor), who is an expert dissemination and implementation (D&I) researcher focused on improving quality of care to vulnerable patient populations with OUD; and Leopoldo Cabassa, PhD, MSW (co-mentor), an expert mixed-methods D&I researcher focused on promoting the physical health of persons with SMI. Additional advisors include: Gerald Cochran, PhD, MSW, a clinical trialist with OUD expertise; Lawrence Palinkas, PhD, an expert in mixed-method designs for D&I research; Angela Presson, PhD, an expert in clinical trials statistical analyses; and Angela Fagerlin, PhD, an expert in patient decision support interventions and in gender equity and diversity in research leadership. People with OUD have a high co-occurrence of serious mental illness (SMI) and other chronic diseases, and are often challenged by their clinical symptoms and social vulnerabilities. While primary care settings frequently treat patients with OUD and SMI, primary care providers have few tools to support this population in self-managing these complex health conditions. Chronic Disease Self-Management programs (CDSMPs) can improve disease management skills and behaviors, but have not been adapted for primary care patients with OUD and SMI. Un-adapted versions might lack relevance to this population and setting. Dr. Siantz will address this implementation gap. This research will support a future hybrid-effectiveness study to test the adapted CDSMP for primary care patients with OUD and SMI. This study’s Specific Aims include: 1) Adapt the CDSMP for adults with OUD and SMI for implementation in a primary care setting using the Collaborative Intervention Planning Framework; 2) Test the feasibility, acceptability, and initial impact of the adapted CDSMP for persons with SMI and OUD in a primary care setting; and 3) Evaluate implementation process and context of the adapted CDSMP using Rapid Assessment Method Informed Clinical Ethnography. This proposed research is significant because it will develop a health education resource for a population at high risk for early mortality. The proposed research is innovative because it will extend an existing CDSMP to a new patient population (persons with OUD and SMI) and novel setting (primary care).

这个K01奖的申请是给伊丽莎白·西恩兹博士的，她是一位受过博士训练的社会工作者