A digital health intervention to increase condom use among adolescent sexual minority males

项目概要/摘要 职业目标：我致力于作为一名独立研究科学家为设计做出贡献， 实施和评估干预措施，以改善青少年性健康，并减少 健康结果的差异。职业发展：该 K99/R00 奖将提供额外的一段时间 指导培训，以支持我在 K99 阶段结束时过渡到独立调查员。我的 培训目标是：（1）掌握进行形成性研究所需的方法策略 健康干预措施的调整和调整； (2) 深入了解青少年性少数群体 男性（ASMM）健康和性自信培训需求； (3) 确定核心原理和应用 实施科学成功地进行了有效性与实施混合的临床试验 设计； (4) 发展技能和专业知识，以促进成功过渡到完全独立的研究 科学家，包括那些需要进行行为干预随机对照试验的科学家。研究 项目：ASMM 感染艾滋病毒/性传播感染的风险极高，且安全套使用率较低 与异性恋同龄人相比。自信的性沟通与更高的性行为率相关 青少年使用安全套；然而，ASMM 没有收到足够的有关性的信息或技能 自信。这项研究的目的是调整现有的数字健康干预措施，最初 旨在向广大青少年提供有关性同意的信息，重点包括 专门针对 ASMM 进行安全套谈判和定制内容。该项目有两个具体目标：（1）适应 性同意干预（PACT）作为基于技能的性自信和安全套谈判 ASMM 培训； (2) 评估 ASMM 中采用的 PACT 干预措施的有效性： 实施混合设计。指导：我组建了专门的专家指导团队 为我提议的研究和培训活动提供持续的指导。该团队包括一名主要 导师（Eric Walsh-Buhi 博士，印第安纳大学公立学院应用健康科学系） Health-Bloomington [IU SPH-B]），二级导师（医学社会系 Kathryn Macapagal 博士） 科学，西北大学范伯格医学院），以及科学顾问小组 印第安纳大学 SPH-B 应用健康科学系（Kristen Jozkowski、Karla Galaviz 和 Debby 博士） 赫本尼克）。未来方向：从此提案中获得的技能和数据将支持未来的 R01 提案 进行 PACT 的进一步试验。

PROJECT SUMMARY/ABSTRACT Career Goal: I am committed to a career as an independent research scientist contributing to the design, implementation, and evaluation of interventions to improve sexual health among adolescents, and reduce disparities in health outcomes. Career Development: This K99/R00 Award will provide an additional period of mentored training to support my transition to an independent investigator by the end of the K99 phase. My training objectives are to: (1) master methodological strategies for conducting formative research necessary for health intervention adaptation and tailoring; (2) gain a proficient understanding of adolescent sexual minority male (ASMM) health and sexual assertiveness training needs; (3) identify core principles and applications of implementation science to successfully conduct a clinical trial with an effectiveness-implementation hybrid design; and (4) develop skills and expertise to facilitate a successful transition into a fully independent research scientist, including those needed to conduct randomized controlled trials of behavioral interventions. Research Project: ASMM are at disproportionately high risk for acquiring HIV/STIs and report lower rates of condom use compared to their heterosexual peers. Assertive sexual communication is associated with higher rates of condom use among adolescents; however, ASMM do not receive adequate information or skills about sexual assertiveness. The purpose of this research is to adapt an existing digital health intervention, originally designed to provide a general population of teens with information about sexual consent, to include a focus on condom negotiation and tailor content specifically for ASMM. The project has two Specific Aims: (1) adapt the sexual consent intervention (PACT) to serve as skills-based sexual assertiveness and condom negotiation training for ASMM; and (2) evaluate the adapted PACT intervention among ASMM in an effectiveness- implementation hybrid design. Mentorship: I have assembled a dedicated mentoring team of experts to provide ongoing guidance on my proposed research and training activities. This team includes a primary mentor (Dr. Eric Walsh-Buhi, Department of Applied Health Science, Indiana University School of Public Health-Bloomington [IU SPH-B]), a secondary mentor (Dr. Kathryn Macapagal, Department of Medical Social Sciences, Northwestern University’s Feinberg School of Medicine), and a panel of scientific advisors in the Department of Applied Health Science at IU SPH-B (Drs. Kristen Jozkowski, Karla Galaviz, and Debby Herbenick). Future Directions: Skills and data acquired from this proposal will support a future R01 proposal to conduct further trials of PACT.