CLINICAL CORE

临床核心

• 批准号: 7318790
• 负责人: MARY J KREEK
• 金额: $ 34.38万
• 依托单位: ROCKEFELLER UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7318790
• 关键词: Area; Buprenorphine; Clinic; Clinical; Clinical Investigator; Clinical Research; Disease; Drug abuse; Environment; Evaluation; Funding; Genetic; Goals; Health Personnel; Heroin Dependence; Human; Informed Consent; Inpatients; Maintenance; Medical; Medicine; Methadone; Molecular Genetics; Molecular Neurobiology; New York; Numbers; Nurse Practitioners; Nurses; Nursing Research; Outpatients; Pharmacotherapy; Physicians; Professional counselor; Psychologist; Purpose; Research; Research Ethics Committees; Screening procedure; Site; Social Workers; Study Subject; Training; Training and Education; Universities; University Hospitals; follow-up; interest; performance site; programs; response

The Clinical Research Core is a fundamental and essential core of our NIH-NIDA funded Center. The goals of the core are: 1) To provide highly trained staff (physicians, nurse practitioners, nurses, and assistants for research) at all levels to perform the rigorous inpatient molecular neurobiology studies as detailed in Project 4, as well as an outpatient site for performance of related genetic studies, as well as for subject screening, evaluation, and follow-up. 2) The second goal is to develop or maintain strong on-site relationships with a limited number of large, successful programs delivering primarily pharmacotherapy for heroin addiction using methadone maintenance or buprenorphine maintenance for: a. Recruitment of subjects for studies at The Rockefeller University Hospital b. In some cases, conducting onsite human molecular genetics ascertainment studies with local clinic IRBs' Informed Consent, as well as Rockefeller University IRB Informed Consent, both signed c. To identify new problems, including psychiatric and medical problems, new drug abuse problems confronting these groups, as well as any unexpected positive or adverse responses to specific treatments. A broad spectrum of subjects in the greater New York area are used for recruitment. Our related clinic in Las Vegas, NV, is used primarily for identification of problems and confirming or refuting the generalizability of observations made in the greater New York area in another part of our nation. 3) The third goal is to provide a nurturing and rigorous environment for the training of clinical investigators, including physicians, nurse practitioners, research nurses, counselors, psychologists, and a wide variety of healthcare personnel, including social workers and counselors interested in becoming directly involved in addictive diseases research or for the purpose of general education and training in research medicine and/or addictive diseases treatment.

临床研究核心是我们NIH-NIDA资助中心的基础和必不可少的核心。目标 核心部分包括： 1)提供训练有素的工作人员(医生、执业护士、护士和研究助理) 进行项目4中详细说明的严格的住院患者分子神经生物学研究的水平，以及 门诊站点，用于相关基因研究的执行以及受试者筛选、评估和 后续行动。 2)第二个目标是与有限数量的大型、 成功的项目主要使用美沙酮维持对海洛因成瘾的药物治疗 或丁丙诺啡维持费： A.在洛克菲勒大学医院招募研究对象 B.在某些情况下，与当地临床IRBs进行现场人类分子遗传学研究 知情同意书，以及洛克菲勒大学IRB知情同意书，均已签署 C.确定新问题，包括精神和医疗问题、新的药物滥用问题 面对这些群体，以及对特定治疗的任何意想不到的积极或不良反应。一个 大纽约地区的广泛科目被用于招聘。我们在拉斯维加斯的相关诊所 拉斯维加斯，内华达州，主要用于识别问题和确认或驳斥的概括性 在我们国家另一个地区的大纽约地区所做的观察。 3)第三个目标是为临床研究人员的培训提供一个培育和严格的环境， 包括内科医生、执业护士、研究护士、咨询师、心理学家和各种各样的 医护人员，包括有兴趣直接参与的社会工作者和顾问 成瘾性疾病研究或用于研究医学和/或研究方面的一般教育和培训 成瘾性疾病治疗。