UK NETT Clinical Site Hub

英国 NTT 临床站点中心

• 批准号: 7417511
• 负责人: Roger Loyd Humphries
• 金额: $ 19.41万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-03 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7417511
• 关键词: Academic Medical Centers; Accident and Emergency department; Acute; Adult; Advanced Cardiac Life Support; Agreement; Air; Ambulances; American College of Surgeons; Brain; Caring; Cities; Clinical Trials; Collaborations; Communication; Community Hospitals; Consent; County; Disease model; Doctor of Medicine; Emergency Medicine; Emergency Situation; Emergency medical service; Emergency treatment; Enrollment; Environment; Evaluation; Faculty; Fire - disasters; Goals; Government; Head; Hospitals; Internet; Investigational Therapies; Kentucky; Medical; Medical Faculty; Medical center; Medicine; Neurological emergencies; Neurology; Operative Surgical Procedures; Patient Recruitments; Patients; Physicians; Positioning Attribute; Principal Investigator; Provider; Randomized; Rehabilitation therapy; Research; Research Infrastructure; Research Personnel; Resources; Rural; Rural Population; Services; Speed; Spinal Cord; Spinal cord injury; Trauma; Universities; University Hospitals; Urban Hospitals; Veterans; base; clinical research site; college; design; experience; member; nervous system disorder; neurosurgery; professor; response; trauma centers; treatment trial

DESCRIPTION (provided by applicant): This proposal describes the establishment of a Neurological Emergencies Treatment Trials (NETT) Network Clinical Site Hub at the University of Kentucky Medical Center (UKMC) in Lexington, Kentucky, in response to NIH/NINDS RFA-NS-06-009. The overall goal of this proposal is to identify UKMC as an academic medical facility with regional affiliate partners adept in "the evaluation of treatments for patients with a broad spectrum of neurological emergencies." The NETT Clinical Site Hub at UKMC is founded upon an intra- institutional collaboration between physician faculty members of the Departments of Emergency Medicine, Neurology, and Neurosurgery. Regional affiliate medical care facilities aligned with UKMC include the Department of Veterans Affairs Medical Center/Cooper Drive Division (DVAMC/CDD) in Lexington and "spoke" community hospitals located in non-urban environments throughout Central and Eastern Kentucky. The following Specific Aims are proposed: 1) To demonstrate the existence of an infrastructure for patient recruitment in "large, simple" clinical trials performed in acute-onset neurological disorders modeled by TBI, drawing upon the resources of a Level 1 Trauma Center situated within a broadly-based geographical network of referring hospitals in non-urban settings and 2) To demonstrate the existence of an infrastructure for patient recruitment in clinical trials performed in acute-onset neurological disorders, requiring Exception to Consent for Emergency Research.

描述(由申请人提供)：本提案描述了根据NIH/NINDS RFA-NS-06-009，在肯塔基州列克星敦的肯塔基大学医学中心(UKMC)建立神经紧急情况治疗试验(NETT)网络临床站点中心。这项提案的总体目标是将UKMC确定为一个学术医疗机构，并与地区附属伙伴合作，擅长“评估对患有广泛神经紧急情况的患者的治疗”。UKMC的NETT临床网站中心是建立在急诊内科、神经科和神经外科的内科教员之间的机构内合作基础上的。与UKMC结盟的地区附属医疗机构包括列克星敦的退伍军人事务部医疗中心/库珀驱动部门(DVAMC/CDD)，以及位于肯塔基州中部和东部非城市环境中的“辐射”社区医院。建议的具体目标如下：1)利用位于基础广泛的非城市地区转诊医院地理网络内的1级创伤中心的资源，证明在TBI模拟的急性起病神经疾病临床试验中存在招募病人的基础设施；2)证明在急性起病神经疾病临床试验中存在招募病人的基础设施，紧急研究需要获得同意才能例外。