UK NETT Clinical Site Hub

描述（由申请人提供）：本提案描述了在肯塔基州列克星敦的肯塔基大学医学中心（UKMC）建立一个神经急救治疗试验（NETT）网络临床站点中心，以响应NIH/NINDS RFA-NS-06-009。该提案的总体目标是将UKMC确定为一个学术医疗机构，与区域附属伙伴合作，擅长“对广泛的神经紧急情况患者的治疗进行评估”。英国医学中心的NETT临床站点中心建立在急诊医学、神经病学和神经外科的内科教员之间的机构内合作基础上。与UKMC结盟的区域附属医疗保健设施包括列克星敦的退伍军人事务部医疗中心/库珀路分部（DVAMC/CDD）和位于肯塔基州中部和东部非城市环境中的“spoke”社区医院。建议的具体目标如下：1)利用位于非城市环境中广泛的转诊医院地理网络中的一级创伤中心的资源，证明在急性发作性神经疾病的临床试验中存在招募患者的基础设施；2)证明存在招募患者的基础设施；要求紧急研究同意例外

DESCRIPTION (provided by applicant): This proposal describes the establishment of a Neurological Emergencies Treatment Trials (NETT) Network Clinical Site Hub at the University of Kentucky Medical Center (UKMC) in Lexington, Kentucky, in response to NIH/NINDS RFA-NS-06-009. The overall goal of this proposal is to identify UKMC as an academic medical facility with regional affiliate partners adept in "the evaluation of treatments for patients with a broad spectrum of neurological emergencies." The NETT Clinical Site Hub at UKMC is founded upon an intra- institutional collaboration between physician faculty members of the Departments of Emergency Medicine, Neurology, and Neurosurgery. Regional affiliate medical care facilities aligned with UKMC include the Department of Veterans Affairs Medical Center/Cooper Drive Division (DVAMC/CDD) in Lexington and "spoke" community hospitals located in non-urban environments throughout Central and Eastern Kentucky. The following Specific Aims are proposed: 1) To demonstrate the existence of an infrastructure for patient recruitment in "large, simple" clinical trials performed in acute-onset neurological disorders modeled by TBI, drawing upon the resources of a Level 1 Trauma Center situated within a broadly-based geographical network of referring hospitals in non-urban settings and 2) To demonstrate the existence of an infrastructure for patient recruitment in clinical trials performed in acute-onset neurological disorders, requiring Exception to Consent for Emergency Research.