Tanzanian Drug Treatment as AIDS Prevention - Reliability and Validity Study

坦桑尼亚药物治疗作为艾滋病预防 - 可靠性和有效性研究

• 批准号: 7756281
• 负责人: Mark L Williams
• 金额: $ 20.31万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-15 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7756281
• 关键词: AIDS prevention; Address; Africa South of the Sahara; Communities; Data; Development; Drug usage; Drug user; Europe; HIV; Heroin; Heroin Dependence; Hour; Injecting drug user; Injection of therapeutic agent; Intake; Interview; Knowledge; Measurement; Measures; Methods; Modification; Motivation; Needle Sharing; Needles; Outcome; Participant; Pharmaceutical Preparations; Phase; Preventive Intervention; Property; Psychometrics; Questionnaires; Readiness; Recommendation; Recruitment Activity; Reporting; Research; Research Project Grants; Sampling; Severities; Sex Behavior; Social Functioning; Structure; Tanzania; Testing; Time; Translating; Translations; Treatment outcome; United States; Validity and Reliability; Visit; Western Europe; addiction; base; design; drug efficacy; improved; innovation; meetings; programs; psychologic; public health relevance; response; social; standardize measure; transmission process; treatment program; vector

DESCRIPTION (provided by applicant): The purpose of this study, the Tanzanian Drug Treatment as HIV/AIDS Prevention Project (D-TAPP) - Reliability and Validity Study, is to conduct formative research necessary to the implement of drug treatment as an HIV prevention intervention in Dar es Salaam, Tanzania. The specific aims of D-TAPP 1) - Reliability and Validity Study are: Aim1: To develop culturally appropriate measures of psychological functioning, social functioning, treatment motivation, addiction severity, and readiness for treatment; Aim 2: To assess IDUs' understanding and relevancy of the measures of psychological functioning, social functioning, treatment motivation, addiction severity, and readiness for treatment; and Aim 3: To test the reliability and validity of the D-TAPP Questionnaire. The D-TAPP - Reliability and Validity Study will be implemented in three components reflecting the three specific aims using a mixed methods design. In component 1, the D-TAPP questionnaire will be translated from English to Swahili and the accuracy of the translations and the content validity of the translated measures will be assessed by a panel of native Swahili-speaking experts. In component 2, semi-structured interview data will be collected from a purposeful sample of 40 IDUs. In this component, the D-TAPP questionnaire will be presented to IDU participants, and they will be asked to assess the understandability and cultural relevancy of each item in the questionnaire (Aim 2). Participants will also be asked to evaluate scales used to record measurement responses. In particular, IDUs will be asked to make recommendations that will improve understandability, cultural relevancy, and response measurement. The questionnaire will be modified to reflect findings produced by the Component 2 study. Component 3 will assess the psychometrics of the measures. Internal and 48 hour test/retest reliability will be determined along with content, construct and criterion related validities. For this study, a purposeful sample of 150 IDUs will be recruited to participate. Data will be collected at intake and 48 hours later. PUBLIC HEALTH RELEVANCE: Tanzanian Drug Treatment as HIV/AIDS Prevention Project (D-TAPP) - Reliability and Validity Study will investigate the psychometric properties of standardized measures of treatment motivation in a sample of Tanzanian injection drug users.

描述（由申请人提供）：坦桑尼亚药物治疗作为艾滋病毒/艾滋病预防项目（D-TAPP）——可靠性和有效性研究的目的是进行必要的形成性研究，以在坦桑尼亚达累斯萨拉姆实施药物治疗作为艾滋病毒预防干预措施。 D-TAPP 1) - 可靠性和有效性研究的具体目标是： 目标 1：针对心理功能、社会功能、治疗动机、成瘾严重程度和治疗准备情况制定适合文化的衡量标准；目标 2：评估吸毒者对心理功能、社会功能、治疗动机、成瘾严重程度和治疗准备程度等指标的理解和相关性；目标 3：测试 D-TAPP 问卷的信度和效度。 D-TAPP - 可靠性和有效性研究将通过三个部分实施，反映使用混合方法设计的三个具体目标。在第 1 部分中，D-TAPP 调查问卷将从英语翻译成斯瓦希里语，翻译的准确性和翻译措施的内容有效性将由斯瓦希里语母语专家小组进行评估。在第 2 部分中，将从 40 名注射吸毒者的有目的样本中收集半结构化访谈数据。在此部分中，将向 IDU 参与者提交 D-TAPP 调查问卷，并要求他们评估调查问卷中每个项目的可理解性和文化相关性（目标 2）。参与者还将被要求评估用于记录测量反应的量表。特别是，注射吸毒者将被要求提出建议，以提高可理解性、文化相关性和反应衡量。调查问卷将进行修改，以反映第 2 部分研究的结果。第 3 部分将评估这些措施的心理测量。内部和 48 小时测试/重新测试的可靠性将与内容、结构和标准相关的有效性一起确定。本研究将有目的地招募 150 名注射吸毒者作为样本参与。数据将在摄入时和 48 小时后收集。公共健康相关性：坦桑尼亚药物治疗作为艾滋病毒/艾滋病预防项目（D-TAPP）——可靠性和有效性研究将调查坦桑尼亚注射吸毒者样本中治疗动机标准化测量的心理测量特性。