A Trial to Test the Efficacy of a Tailored Intensive Smoking Cessation Interventi

测试定制强化戒烟干预效果的试验

• 批准号: 7677780
• 负责人: Jonathan Shuter
• 金额: $ 21.34万
• 依托单位: MONTEFIORE MEDICAL CENTER (BRONX, NY)
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-15 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7677780
• 关键词: Abstinence; Address; Adverse effects; Alcohol consumption; Behavior Therapy; Behavioral; Cardiac; Caring; Characteristics; Clinical Practice Guideline; Clinical Trials; Communities; Comorbidity; Counseling; Data; Dependence; Educational Curriculum; Effectiveness; Epidemic; Evaluation; Event; Funding; Generic Drugs; Goals; HIV; Incidence; Intervention; Life; Malignant Neoplasms; Modeling; Morbidity - disease rate; Motivation; Neighborhoods; Persons; Pharmaceutical Preparations; Pharmacotherapy; Population; Prevalence; Provider; Public Health; Published Comment; Randomized Controlled Trials; Research; Research Personnel; Resources; Science; Smoke; Smoker; Smoking Cessation Intervention; Social Environment; Social Network; Social support; Testing; Tobacco; Tobacco use; Treatment outcome; United States National Institutes of Health; United States Public Health Service; aging population; base; biopsychosocial; cigarette smoking; design; effective intervention; efficacy testing; evidence base; group intervention; improved; knowledge base; peer; post intervention; prevent; programs; psychosocial; public health relevance; reduce tobacco use; smoking cessation; social cognitive theory; standard care; symposium; tobacco prevention

DESCRIPTION (provided by applicant): The 2006 NIH State-of-the-Science Conference Statement on Tobacco Use: Prevention, Cessation, and Control emphasized the need to "tailor interventions for different populations because generic treatments may not be appropriate for everyone," and to determine the effectiveness of cessation activities in populations with high rates of tobacco use and other comorbidities. They identified the HIV-infected community as a high priority target for these efforts. More than half of persons with HIV (PWHs) in the US smoke cigarettes, and incidence rates of cardiac events and tobacco related cancers are rising in this group at an alarming rate. The psychosocial profile of the HIV-infected community, characterized by high rates of psychiatric comorbidity, drug and alcohol use, and low levels of social support, suggests that achieving high cessation rates will be a great challenge. The main goals of this proposal are to (1) develop and pilot a tailored, multicomponent, intensive smoking cessation intervention for PWHs based upon a body of behavioral data that the investigators have collected in a preliminary study, and (2) perform a randomized, controlled study in PWH smokers to determine the efficacy of the tailored intervention in achieving three month, point-prevalence abstinence from tobacco use. The long term objectives of the proposed study are to expand the available knowledge base on smoking cessation in PWHs, and to develop an intensive smoking cessation program curriculum appropriate for PWHs throughout the nation. PUBLIC HEALTH RELEVANCE: The epidemic of cigarette smoking superimposed upon an aging population of persons living with HIV (PWHs) and its associated comorbidities represents an emerging public health crisis. PWH smokers have few, if any, smoking cessation resources available to them that are tailored to their needs, and their care providers have virtually no studies upon which to build an evidence-based approach to achieving abstinence. This proposal, if funded, will begin to address these critical needs.

描述（由申请人提供）：2006年美国国立卫生研究院关于烟草用途：预防、戒烟和控制的科学现状会议声明强调，需要“针对不同人群定制干预措施，因为通用治疗可能不适合所有人”，并确定戒烟活动在烟草使用率高和其他合并症人群中的有效性。他们将艾滋病毒感染社区确定为这些努力的高度优先目标。在美国，超过一半的艾滋病毒感染者（PWHs）吸烟，心脏病和烟草相关癌症的发病率正在以惊人的速度上升。艾滋病毒感染社区的社会心理状况，其特点是精神病合并症、吸毒和酗酒的比例很高，社会支持水平很低，这表明实现高戒烟率将是一个巨大的挑战。该提案的主要目标是：（1）根据研究人员在初步研究中收集的大量行为数据，为PWH制定并试行定制的、多组分的、强化的戒烟干预措施;（2）在PWH吸烟者中进行随机对照研究，以确定定制干预措施在实现3个月、点流行率戒烟方面的有效性。拟议研究的长期目标是扩大PWH戒烟的现有知识基础，并制定适合全国PWH的强化戒烟计划课程。公共卫生相关性：吸烟的流行加上艾滋病毒感染者（PWHs）及其相关合并症的人口老龄化，是一个新出现的公共卫生危机。威尔斯亲王医院的吸烟者几乎没有任何针对他们需要的戒烟资源，他们的护理提供者几乎没有任何研究来建立一个以证据为基础的方法来实现戒烟。这项建议如果得到资助，将开始满足这些关键需求。