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Studies of Alpha-tocopherol and Beta-Carotene in Finland

Studies of Alpha-tocopherol and Beta-Carotene in Finland
芬兰对α-生育酚和β-胡萝卜素的研究
批准号：
7593216
负责人：
Demetrius Albanes
金额：
$207.3万
依托单位：
DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/7593216
关键词：
AgeBeta CaroteneCaroteneCessation of lifeDailyEnd PointFinlandIncidenceInstitutesInterventionMalignant NeoplasmsMalignant neoplasm of lungPlacebosPublic HealthRandomizedRecruitment ActivitySmokerSupplementationTocopherolsVitamin E Acetatealpha Tocopheroldayfollow-upmalemen

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中文摘要
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英文摘要
Male smokers between the ages of 50 and 69 were recruited from southwestern Finland between April 1985 and June 1988. A total of 29,133 men were randomly assigned to one of four intervention groups: 50 mg/day a-tocopherol (as dl-a-tocopheryl acetate); 20 mg/day b-carotene; both a-tocopherol and b-carotene; or placebo. They were followed for five to eight years during the trial, until death, or 30 April 1993 when intervention was stopped (median follow-up, 6.1 years). Follow-up for endpoints was continued postintervention.
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