Farm Worker Family Health Cohort Study

描述（由申请人提供）： 雇佣的农场工人为加州的劳动密集型农业部门提供了大部分劳动力，他们也承受着最大的健康负担。加州的雇佣农场工人面临着呼吸系统疾病、肌肉骨骼问题、传染病、与压力有关的精神健康障碍和与生活方式有关的疾病如肥胖症的发病率和死亡率增加的风险。有很少的研究，以病因学的不良健康结果，发生在这一人群中不成比例。该项目的总体目标是继续对加州通过NIOSH补充资金建立的一组雇佣农场工人家庭进行纵向随访。我们建议对加州门多塔的MICASA研究队列进行两次随访评估，以评估该人群的疾病发病率和患病率。这些后续评估将对构成我们在门多塔的农场工人队列的400个家庭进行。在五年的研究期间，将对所有MICASA研究参与者（户主和配偶）进行两次访谈。我们还将在人群中进行肺功能测试，测量生命体征并在两个时间段进行人体测量。最后，接触评估部分将收集关于这一人群中颗粒物接触的定量数据。本研究的具体目的是：1）测量呼吸道症状和农业伤害的发生率，并评估农业暴露和生活方式因素与呼吸道症状、农业伤害和肌肉骨骼问题的独立关联; 2）检查特应性、哮喘和哮喘症状的患病率和决定因素; 3）确定我们人口中农业工人通常从事的任务和作物的颗粒物暴露水平;四、检查突发呼吸道症状和肺功能随时间的变化，并评估职业因素等预测因素与突发事件之间的关系。症状和肺功能的变化。这种方法使我们能够解决各种影响健康的因素，包括工作，家庭环境和个人健康行为。建立这一队列是为了提高对重要健康风险的认识，为设计有效的公共卫生和临床干预措施提供基础，并最终改善这一得不到充分服务的人口的健康。

DESCRIPTION (provided by applicant): Hired farm workers provide the majority of the workforce for California's labor-intensive agricultural sector, and they also suffer the greatest health burden. California's hired farm workers face increased risks of morbidity and mortality from respiratory disease, musculoskeletal problems, infectious diseases, stress- related mental health disorders and lifestyle-related diseases such as obesity. There has been very little research into the etiology of the poor health outcomes that occur disproportionately in this population. The overall goal of this proposed project is to continue with a longitudinal follow-up of a cohort of hired farm worker families in California that was established through supplemental funding from NIOSH. We propose to conduct two follow-up assessments of the MICASA study cohort in Mendota, California to assess the incidence and prevalence of diseases in this population. These follow-up assessments will be conducted on the 400 families comprising our farm worker cohort in Mendota. Interviews will be conducted with all MICASA study participants (both the head of household and spouse) twice during the five-year study period. We will also conduct pulmonary function testing, measure vital signs and take anthropometric measurements at two time periods in the population. Finally, the exposure assessment component will collect quantitative data on particulate exposure in this population. The specific aims of the study are to: 1) measure the incidence of respiratory symptoms and agricultural injuries and assess the independent association of agricultural exposures and lifestyle factors to respiratory symptoms, agricultural injuries, and musculoskeletal problems; 2) examine the prevalence and determinants of atopy, asthma and asthma symptoms; 3) determine levels of particulate matter exposure for tasks and crops commonly conducted by agricultural workers in our population; 4) examine incident respiratory symptoms and changes in pulmonary function over time and assess the relationship between predictors such as occupational factors with incident symptoms and changes in pulmonary function. This approach allows us to address a wide range of factors affecting health including work, home environment, and personal health behaviors. This cohort is being established to improve understanding of important health risks and to provide a basis for the design of effective public health and clinical interventions, and ultimately to improve the health of this underserved population.