PEDIATRIC LATE OUTCOMES PROTOCOL

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to follow children and adolescents who are currently enrolled in or were previously enrolled in pediatric ACTG treatment perinatal or drug research studies to look for any late consequences of therapy in growth, neurologic and neuropsychologic function, long term survival, and quallity of life. There are several key hypotheses listen below that this late outcomes protocol plans to address in relation to pediatric interventions. In addition, it is also anticipated that the longitudinal data gathered in this protocol will enable investigators in the pediatric ACTG to answer other research questions and hypotheses specific to treatment in perinatal protocols in which they are involved.