Chinese Dementia Care Research Center

描述(申请人提供)：随着人口的迅速老龄化，中国面临着不可避免的与年龄相关的疾病增加。最近的一项流行病学研究发现，65岁及以上的人中阿尔茨海默病的患病率为4.85%，血管性痴呆的患病率为1.1%；因此，中国不是痴呆症的低风险国家。痴呆症是中国面临的重大社会和健康挑战，专家们一致认为，提高向痴呆症患者及其照顾者提供的护理质量至关重要，并制定有助于发展循证护理的研究项目。目前，支持这类方案的发展和制度化的基础设施有限。这个R21应用程序提出了一个独特的合作方案，致力于提高中国的痴呆症研究和护理能力，通过建立和扩大北京大学精神卫生研究所、武汉大学公共卫生学院、布里格姆妇女医院/哈佛医学院精神病学系和西弗吉尼亚大学的研究人员之间的现有合作。具体项目目标是：1)在北京大学附属医院建立跨学科痴呆症护理研究中心，由来自世卫组织/北京精神卫生研究与培训合作中心、国家精神卫生中心、中国、疾控中心等中国顾问的主要合作者和来自世界各地知名学术中心的中国顾问共同参与；2)在西大-圣何塞医院建立跨学科痴呆症护理研究中心，由北大-玛格丽特医院和来自美国的专家提供培训；3)为痴呆症护理方面的卫生专业人员和家庭护理人员提供可持续的培训能力；3)通过标准化数据库开发和研究管理方面的培训，提高北大-IMH和WHU-SHP的研究能力；以及，4)对痴呆症的解释性模型进行初步研究，并为未来的R01应用制定干预策略。调查人员乐观地认为，由于参与实体(包括政府/公共卫生机构、学术机构、临床中心和非政府组织)对改善痴呆症患者及其照顾者的生活的坚定承诺，由FIC支持开发的合作研究和培训基础设施可能会在计划资金结束后很长一段时间内持续下去。公共卫生相关性：该项目将提供中国痴呆症患病率以及与照料相关的负担的信息。因此，这些信息将有助于向政府通报公共卫生政策的必要变化，以便有效地应对日益增加的痴呆症护理负担。

DESCRIPTION (provided by applicant): With its rapidly aging population, China faces an inevitable increase in age-related diseases. A recent epidemiological study found a 4.85% prevalence of Alzheimer's disease among individuals aged 65 and over, and a 1.1% prevalence of Vascular Dementia; thus, China is not a low risk nation for dementia. Dementia is a significant social and health challenge for China, with experts in agreement that it is critical to improve the quality of care provided to persons with dementia and their caregivers, and to develop research programs that contribute to the development of evidence based care. Currently, limited infrastructure exists to support the development and institutionalization of such programs. This R21 application proposes a unique collaboration dedicated to enhancing the capacity for dementia research and care in China, by building upon, and expanding existing collaborations among investigators at the Peking University Institute of Mental Health (PKU-IMH), Wuhan University School of Public Health (WHU-SPH), the Department of Psychiatry at Brigham and Women's Hospital/Harvard Medical School, and West Virginia University. Specific project aims are to: 1) establish the interdisciplinary Dementia Care Research Center (DCRC) at the PKU-IMH, with primary Chinese collaborators from WHO/Beijing Collaborating Center for Research and Training on Mental Health, and the National Center for Mental Health, China, CDC, and other Chinese consultants from eminent academic centers around the world; 2) develop the interdisciplinary Dementia Care Research Center at WHU-SPH, with training provided by PKU-IMH and experts from the U.S.; 3) enable sustainable training capacity for health professionals and family caregivers in dementia care; 3) increase research capability at PKU-IMH and WHU-SHP through training in standardized database development and research management; and, 4) conduct pilot studies of explanatory models of dementia and develop intervention strategies for a future R01 application. The investigators are optimistic that the collaborative research and training infrastructure developed as a result of FIC support will likely be sustained long after the end of program funding because of the strong commitment of the participating entities, including governmental/public health agencies, academic institutions, clinical centers, and NGOs, to improving the life of elders with dementia and their caregivers. PUBLIC HEALTH RELEVANCE: This project will provide information of the prevalence of dementia in China and on the burden associated with caregiving. This information will thus serve to inform the government of changes necessary to public health policy in order to effective cope with the ever increasing burden of dementia caregiving.