PHASE III RANDOMIZED TRIAL PREOP CHEMO VS CHEMO/RADIO/SURGERY FOR LUNG CANCER

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 肺癌患者将被招募到这项研究中。以前的研究数据表明，化疗后手术似乎比单纯手术产生更好的应答率，然而，目前，手术后化疗加放疗的作用尚未得到测试。 这项研究的目的是比较两种治疗方法对肺癌患者的疗效，无论是好的还是坏的，以找出哪种治疗方法更好。这两种治疗方法是： 化疗后再做手术 化疗和放疗后再做手术 这项研究的受试者将接受上述治疗中的一种；而不是两种。然而，所有受试者都将在手术后接受化疗。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Participants with lung cancer will be recruited to this study. Data from previous studies suggests that chemotherapy followed by surgery seems to produce better response rates over surgery alone however, at this time, the role of chemotherapy plus radiation after surgery has not been tested. The purpose or this study is to compare the effects, good and/or bad, of two treatments on subjects with lung cancer to find out which is better. The two treatments are: Chemotherapy followed by surgery Chemotherapy and radiation followed by surgery Subjects in this study will get one of the above treatments; not both. However, all subjects will receive chemotherapy after surgery.