DRUG INTERACTIONS OF MILK THISTLE

水飞蓟的药物相互作用

• 批准号: 7607163
• 负责人: JOHN C MARKOWITZ
• 金额: $ 0.05万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607163
• 关键词: Affect; Antioxidants; Botanicals; Cells; Chemicals; Computer Retrieval of Information on Scientific Projects Database; Condition; Disease; Drug Interactions; Excretory function; Flavonoids; Funding; General Population; Goals; Grant; Institution; Life; Liver; Metabolism; Milk Thistle; Pharmaceutical Preparations; Plants; Prostate; Research; Research Personnel; Resources; Scientist; Source; Tissues; United States National Institutes of Health; fruits and vegetables; prescription document; prescription procedure

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This research is being sponsored by the National Institutes of Health (NIH). It is recognized that the plant or botanical supplement known as Milk Thistle is used by the general public as an alternative treatment for various diseases affecting the liver and prostate. Milk Thistle, like most plants, vegetables and fruits contains natural chemicals called flavonoids that in many cases provide protection to living cells and tissues by being antioxidants. Additionally, it is believed by scientists at the NIH that Milk Thistle may be a worthwhile treatment for some conditions and formal studies are being planned. The goal of this study is to determine if taking a Milk Thistle will affect the breakdown and excretion (metabolism) of other prescription medications when Milk Thistle is taken together with these medications.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这项研究由美国国立卫生研究院（NIH）赞助。 人们认识到，被称为牛奶蓟的植物或植物补充剂被公众用作影响肝脏和前列腺的各种疾病的替代治疗。像大多数植物一样，牛奶蓟，蔬菜和水果含有天然化学物质，称为类黄酮，在许多情况下，通过抗氧化剂为活细胞和组织提供保护。 此外，美国国立卫生研究院的科学家认为，水飞蓟可能是治疗某些疾病的一种有价值的方法，正式的研究正在计划中。这项研究的目的是确定是否采取奶蓟将影响其他处方药的分解和排泄（代谢）时，奶蓟与这些药物一起服用。