GENE EXPRESSION IN PEDIATRIC ARTHRITIS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究的主要目的是建立幼年类风湿性关节炎和幼年脊柱关节病(JRA/JspA)的遗传学基础，这是儿童最常见的慢性关节病。该方法将使用综合基因组学来确定可能具有遗传基础的3个因素--易感性、临床结果和治疗反应。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary objective of this study is to establish the genetic basis for juvenile rheumatoid arthritis and juvenile spondyloarthropathy (JRA/JspA), the most common chronic arthropathies of childhood. The approach will use integrated genomics to identify 3 elements that are likely to have a genetic basis-susceptibility, clinical outcome, and responses to treatment.