A RANDOMIZED, OPEN-LABEL, MULTI-CENTER PHASE II STUDY TO EVALUATE THE SAFETY

评估安全性的随机、开放标签、多中心 II 期研究

• 批准号: 7608372
• 负责人: CATERINA MINNITI
• 金额: $ 3.05万
• 依托单位: CHILDREN'S RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7608372
• 关键词: Allergic Reaction; Chelating Agents; Child; Chronic; Computer Retrieval of Information on Scientific Projects Database; Deferoxamine Methanesulfonate; Funding; Grant; Institution; Iron Overload; Label; Oral; Phase; Randomized; Research; Research Personnel; Resources; Safety; Source; Toxic effect; Transfusion; United States National Institutes of Health; novel

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a study looking at the efficacy and toxicities of a novel oral chelator for children with iron overload due to chronic transfusion. The compound can be used in cases of allergic reaction to Desferal or when compliance is an issue.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这是一项研究，旨在观察一种新型口服螯合剂对因慢性输血而导致的铁超载儿童的疗效和毒性。该化合物可用于对Desferal的过敏反应或依从性问题。