Mitochondrial Damage following Fetal Hypoxia or Birth Asphyxia: Using Creatine to Preserve Mitochondrial Function

胎儿缺氧或出生窒息后的线粒体损伤：使用肌酸保护线粒体功能

• 批准号: nhmrc : GNT1124493
• 负责人: Dr Hayley Dickinson
• 金额: $ 83.87万
• 依托单位: RMIT University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/mitochondrial-damage-following-mitochondrial-function/1347414
• 关键词: Mitochondrial; Damage; following; Fetal; Hypoxia

There is a need for a therapy that can be given before a mother gives birth to protect the baby should ‘oxygen starvation’ threaten the baby’s brain and other organs such as the heart, kidney, lungs, and the ability to breathe properly. We are suggesting that an increased intake of creatine is a very effective treatment against this threat, and its proven safety and ease of use recommends it for wide application, particularly in countries where the access to medical resources is poor.

如果“缺氧”威胁到婴儿的大脑和其他器官，如心脏、肾脏、肺部，以及正常呼吸的能力，需要在母亲出生前给予一种治疗来保护婴儿。我们建议，增加肌酸的摄入是对抗这种威胁的一种非常有效的治疗方法，它的安全性和易用性已得到证实，建议广泛应用，特别是在医疗资源匮乏的国家。