Neonatal Sucking Organization After Epidural Analgesia

硬膜外镇痛后新生儿吸吮组织

• 批准号: 7545538
• 负责人: ALEECA F BELL
• 金额: $ 2.33万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-01-16 至 2009-08-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7545538
• 关键词: Absence of pain sensation; Acute; Analgesics; Animal Model; Attenuated; Behavioral; Birth; Birth Rate; Breast Feeding; Comparative Study; Development; Devices; Endocrine; Epidural Analgesia; Exposure to; Glucocorticoids; Goals; Healthy People 2010; Hour; Hydrocortisone; Incidence; Infant; Infant Behavior; Intramuscular; Learning; Life; Link; Measures; Mothers; Motor; Neonatal; Oral; Outcome Measure; Pain; Pain management; Perception; Perinatal Exposure; Pharmaceutical Preparations; Physiological; Placenta; Process; Publishing; Randomized; Reporting; Research; Rewards; Salivary; Sensory; Stress; Structure of umbilical artery; System; Systems Biology; United States; Urban Hospitals; Vaginal delivery procedure; acute stress; alertness; behavior measurement; biological adaptation to stress; critical period; dosage; experience; feeding; fetal; innovation; instrument; maternal stress; neonate; neurobehavioral; prenatal stress; pressure; sucking

The primary aim of this two group comparative study is to examine the relationship between fetal exposure to maternal epidural analgesia during labor and measures of neonatal neurobehavioral organization (behavioral state and sucking organization) in the initial feeding at one hour post birth. The associated effects of epiduralanalgesia on sucking organization have not been previously measured. The secondary aim is to examine the relationship between maternaland fetal acute stress responses (cortisol) during labor, and neonatal behavioral state and sucking organization. This research is innovative in exploring whether an attenuated fetal stress response during the criticalperiodof rapidadaptation after birth is a vulnerable link in the initial development of sucking organization afterbirth. These findings will beaninitial step in examining the mechanisms, and perturbations, of early neonatal neurobehavioral organization. Any disruption in the development of neonatal neurobehavioral organization has the potential to alter mother-infant interaction, and the establishment of successfulbreastfeeding, especially in vulnerable dyads.

这两组比较研究的主要目的是检查胎儿暴露之间的关系

项目成果

Maternal and umbilical artery cortisol at birth: relationships with epidural analgesia and newborn alertness.

出生时母体和脐动脉皮质醇：与硬膜外镇痛和新生儿警觉性的关系。

• DOI: 10.1177/1099800411413460
• 发表时间: 2012
• 期刊: Biological research for nursing
• 影响因子: 2.5
• 作者: Bell,AleecaF;White-Traut,Rosemary;Wang,EdwardC;Schwertz,Dorie
• 通讯作者: Schwertz,Dorie